ABSTRACT
Mycetoma is a localized chronic, suppurative, and deforming granulomatous disorder of subcutaneous tissue, skin and bones. Mycetoma is endemic in tropical and subtropical areas, where it is a real public health issue. It is a rare and neglected disease in our country. Etiological classification divides it into eumycetoma caused by fungus, and actinomycetoma caused by bacteria. Since the treatment of these two etiologies is completely different, a definite diagnosis after microbiological and histopathological examination, though difficult, is important. The disease is notoriously difficult to treat. Eumycetoma may be unresponsive to standard antifungal therapy. Authors report a case of eumycetoma in a 38 year-old male from Bihar, with history of thorn prick 30 yrs back. Madurella mycetomatis was isolated from the granular discharge from sinuses and itraconazole was given followed by surgical debridement of the lesion. The patient recovered well and is still on follow up.
ABSTRACT
Mucormycosis is considered one of the most rapidlyprogressing and fulminant forms of fungal infection whichusually begins in the nose and paranasal sinuses followinginhalation of fungal spores. It is caused by organisms ofphylum Zygomycota, the subphylum Mucormycotina whichinclude genera Absidia, Mucor, Rhizomucor, Rhizopus etc. Theincidence of mucormycosis is approximately 1.7 cases per1,000,000 inhabitants per year. Mucormycosis affecting themaxilla is not rare because of rich blood vessel supply to themaxillofacial areas. Most common form of this infection is seenin the rhinomaxillary region and in patients with compromisedimmunity such as diabetes. Hence, early diagnosis of thispotentially fatal disease and prompt treatment is of primeimportance in reducing the mortality rate.