Turner syndrome in a neonate

Turner's syndrome (TS) is the common chromosomal abnormality. However, it is diagnosed rarely in the neonatal period. In many cases the diagnosis of TS may be delayed until childhood, when evaluation for short stature yields the diagnosis, or adolescence, when combination of growth failure and pubertal delay suggests the possibility of TS. Girls with TS are usually treated with growth hormone and oestrogen replacement therapies for short stature and oestrogen deficiency. A multidisciplinary team is usually required for management. Authors report an 11 day old infant who was diagnosed as Turner's syndrome. The classic clinical feature, lymphoedema clinched the diagnosis in our case which was confirmed by chromosomal analysis. The infant was discharged and asked to follow up for regular growth monitoring and parents were counselled regarding the condition.

Prevalence Of Shin Splint In Recreational Marathon Runner

Background: It is essential to find out the presence of shin splint in recreational marathon runners to prevent the injury from causing more damage. This study was conducted to identify shin splint in recreational marathon runners in Krishna Hospital, Karad. This study was designed to provide meaningful insight into the cause of shin splint in recreational marathon runners. Objectives of the study were to find out the impact of shin splint in recreational marathon runners and to assess the severity of shin splint in recreational marathon runners of age group 20-30 years both males and females in Krishna Hospital, Karad. Material and Methods: 190 recreational marathon runners who fit in the criteria were given Runner’s Questionnaire and were asked to fill it. Result: There was marked significance pain was present during(p=0.04) and running throughout(p<0.0001) in recreational marathon runners. Conclusion: It was concluded from the present study that there is a prevalence of shin splint in marathon runners. Shin splint was found more in females (55.3%)than in males (44.7%). Based on the duration of pain and shoe surface was found to be more prevalent to cause shin splint in marathon runners.

Effect Of Resisted Exercises And Aquatic Exercises In Post Traumatic Wrist Stiffness.

Background: The purpose of this study was to assess the effectiveness of resisted exercises and aquatic exercises in post traumatic wrist stiffness. Method: 30 subjects of post traumatic wrist stiffness were included in this study. Following the data collection, the subjects were allotted into 2 groups, Group A – Conventional treatment along with aquatic exercises and Group B – Conventional treatment along with resisted exercises. Before and After the treatment protocol subjects were assessed by Goniometer for range of motion and PRWE Scale, these outcome measures were analysed. Result: Pre and Post treatment protocol was analysed using paired t test and unpaired t test. Analysis for range of motion (p= <0.0001), PRWE (p= <0.0001). Conclusion: Aquatic therapy with conventional therapy i.e. (paraffin wax bath and mobilization) enhances the range of motion of wrist and reduces pain and increases the strength and movement and activity of wrist.

Malignant Melanoma: A Case Report With Literature Review.

Primary malignant melanoma of the oral cavity is a rare and aggressive neoplasm. They tend to metastasize or locally invade tissue more readily than other malignant tumours in the oral region. Prognosis of oral melanoma is comparatively poor and so an early diagnosis and follow-up is critical. Here we report a case of oral melanoma, pigmented macular type, in maxillary anterior gingival region in a 60 year old female patient.

Mucoepidermoid Carcinoma-Histopathologist Perspective– A Review

Mucoepidermoid carcinoma is the most common malignancy of the salivary glands. It comprises 5–10% of all salivary gland tumours. It is histologically comprised of a mixture of mucous cells, intermediate cells, squamoid or epidermoid cells. This tumour may also demonstrate clear cell, oncocytic or columnar cells. There is arguably no other salivary gland tumour in which grading is as important to prognosis and therapy. Here we present a review with systematic approach to the histopathologic diagnosis, grading and prognosis, with a special emphasis on the biologic potential based on newer investigative modalities from the histopathologist perspective.

Brain metastases from breast cancer: management approach.

Brain metastases are a significant cause of morbidity and mortality in patients with breast cancer. HER-2 positivity is an increasingly recognized risk factor for the development of brain metastases. Although considerable progress has been made in the treatment of this complication, supportive measures like steroids, anti-seizure medication and whole-brain radiation remain the cornerstones of management in the majority of patients. The current review discusses the above and other issues like surgical excision, stereotactic radiotherapy, adjuvant radiation, radiosensitization and chemotherapy. A brief discussion of the recent evidence for the use of 'HER-1/ HER-2'-targeted therapy is also present.