ABSTRACT
Aortic dissection is a life-threatening disease that requires immediate surgical intervention. Marfan syndrome is a hereditary disease with an autosomaldominant transmission, which affects the connective tissue, with skeletal, cardiovascular and ocular involvement. It is one of the most prevalent connective tissue disorders, presenting a risk of aortic dissection of approximately 1% even without dilatation of the aorta. When dissectionoccurs during pregnancy and requires surgical intervention (type A dissection), maternal mortality is high (20%-30%). We report a 38 year-old woman with Marfan syndrome that hadan acute type A aortic dissection and severe aortic regurgitation at 37 weeks of gestation. The patient underwent a cesarean section and delivered a healthy baby. Afterwards, aortic valverepair and ascending aortic replacement was successfully performed under circulatory arrest with deep hypothermia. Additionally mitral valve repair for degenerative disease with posterior, autologous pericardium mitral valve ring was performed.
Subject(s)
Adult , Female , Humans , Pregnancy , Aortic Dissection/complications , Aortic Aneurysm/complications , Marfan Syndrome/complications , Pregnancy Complications, Cardiovascular , Aortic Dissection/surgery , Aortic Aneurysm/surgery , Marfan Syndrome/surgery , Pregnancy Complications, Cardiovascular/surgeryABSTRACT
Introducción: En EE.UU. el cáncer de vejiga representa la quinta causa más frecuente de cáncer. El carcinoma urotelial es el tipo histológico más frecuente. RTU asociado a inmunoterapia es el tratamiento de elección. El objetivo de este trabajo es caracterizar una muestra de pacientes con cáncer superficial de vejiga. Materiales y método: Se realizó un estudio descriptivo retrospectivo de 48 fichas clínicas seleccionadas del período 2002-2006. Resultados: De la muestra 77 por ciento correspondió a hombres. Un 90 por ciento presentó cáncer de urotelio. La ubicación más frecuente fue multifocal. La RTU fue el tratamiento más utilizado. Conclusiones: La mayoría de nuestros datos fueron similares a lo descrito en otras publicaciones. La muestra pequeña o un factor económico podría explicar el bajo uso de RTU asociado a inmunoterapia.
Introduction: Bladder cancer is the fifth most frequent type of cancer in the United States of America. Urothelial carcinoma being the most common histological type. TUR in association with immunotherapy is the treatment of choice. The objective of this study is to characterize a group of patients with superficial bladder cancer. Materials and Method: 48 clinical records were used to perform a descriptive retrospective study during a period between 2002-2006.Results: 77percent of cases were men. 90percent presented urothelial carcinoma. The most frequent location was multifocal. TUR was the clinical intervention that was most utilized. Conclusions: The majority of our results are similar to those seen in other publications. he small size of the group or an economical factor might explain the limited use of combined TUR - immunotherapy.
Subject(s)
Humans , Male , Female , Hospitals/statistics & numerical data , Urinary Bladder Neoplasms/epidemiology , Urinary Bladder Neoplasms/pathology , Urinary Bladder Neoplasms/therapyABSTRACT
Introducción: Los tumores testiculares germinales son la neoplasia maligna más frecuente en hombres jóvenes. La incidencia varía por región geográfica. Es altamente curable. El objetivo de este trabajo fue caracterizar a los pacientes y calcular la tasa de incidencia. Materiales y método: Se realizó un estudio descriptivo retrospectivo de 136 fichas clínicas en el período 2003-2008.Resultados: La edad promedio fue de 32,8 años. Un 57 por ciento correspondieron a seminoma, 28 por ciento no seminoma y 14 por ciento mixtos. Un 8 por ciento fueron bilaterales. La tasa fue de 11 por 100.000 habitantes mayores de 15 años. Conclusiones: La mayoría de nuestros datos fueron concordantes con lo descrito en otras publicaciones. La incidencia de cáncer testicular es mayor a la descrita en otras regiones de Chile y del mundo.
Backgrounds: Germ cell tumors of the testicle are the most frequent malignant neoplasm in young men. The incidence varies between geographical regions. This neoplasm is highly curable. The objective of this study was to characterize the patients and calculate the incidence rate. Methods: A descriptive retrospective study was performed with 136 medical histories in the 2003-2008 period. Results: The average age was 32.8 years. 57 percent corresponded to seminomas, 28 percent to non-seminomas and 14 percent were mixed germ cell tumors.8 percent were bilateral. The rate was 11 per 100.000 inhabitants over 15 years. Conclusions: The majority of our results were similar to those described in other publications. The incidence of testicular cancer is higher than the incidence described in other regions of Chile and the world.