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2.
Indian J Physiol Pharmacol ; 1995 Oct; 39(4): 423-4
Article in English | IMSEAR | ID: sea-107485

ABSTRACT

Pain thresholds were recorded in rats by progressive increase in electrical stimulation to induce tail withdrawal, vocalisation and vocalisation after discharge. It was observed that castration resulted in significant reduction of pain threshold which however returned to normal level on substitution with testosterone therapy.


Subject(s)
Animals , Electric Stimulation , Male , Mice , Nociceptors/drug effects , Orchiectomy , Pain Measurement , Pain Threshold/physiology , Rats , Testosterone/administration & dosage , Vocalization, Animal/drug effects
3.
Indian J Physiol Pharmacol ; 1994 Jan; 38(1): 51-2
Article in English | IMSEAR | ID: sea-107901

ABSTRACT

Rats were subjected to immobilization stress of varying duration and their pain thresholds were recorded. It was seen that stress of lesser duration did not affect the endogenous opioid analgesic system while stressor of longer duration stimulated this system to its maximum irrespective of further increasing the duration of the stress condition even upto two fold.


Subject(s)
Animals , Endorphins/physiology , Immobilization , Male , Pain Measurement , Pain Threshold/physiology , Rats , Stress, Psychological/physiopathology , Time Factors , Vocalization, Animal/physiology
4.
Indian J Physiol Pharmacol ; 1993 Oct; 37(4): 333-6
Article in English | IMSEAR | ID: sea-107890

ABSTRACT

Effects of intrastriatal injections of haloperidol (Dopamine antagonist) and D-amphetamine (Dopamine agonist) on lordosis behaviour were studied in ovariectomized female albino rats, after priming with subcutaneous injections of estrogen and progesterone. The lordosis quotient (LQ) significantly increased after haloperidol, and decreased following D-amphetamine treatment. However, the inhibitory effect of D-amphetamine was transient and could be reversed by haloperidol in the same animal when given one hour after the D-amphetamine injection. The ovarian hormones probably act centrally to suppress the DA system in the striatum thereby enhancing the tonic and dorsal immobility responses associated with lordosis.


Subject(s)
Animals , Corpus Striatum/physiology , Dextroamphetamine/pharmacology , Dopamine/metabolism , Estradiol/pharmacology , Female , Haloperidol/pharmacology , Injections, Subcutaneous , Ovariectomy , Posture , Progesterone/administration & dosage , Rats , Sexual Behavior, Animal/drug effects
5.
Indian J Exp Biol ; 1993 Jul; 31(7): 638-40
Article in English | IMSEAR | ID: sea-61003

ABSTRACT

Male rats were exposed to four different stress conditions, varying in duration and intensity, during separate periods and their copulatory behaviour was studied. The number of mounts and time spent in other sexual behaviours were reduced with intensity of stressor being primarily responsible rather than prolongation of duration of a less severe stress condition.


Subject(s)
Animals , Female , Male , Rats , Sexual Behavior, Animal , Stress, Physiological , Time Factors
6.
Indian J Physiol Pharmacol ; 1993 Jan; 37(1): 40-4
Article in English | IMSEAR | ID: sea-107065

ABSTRACT

Changes in blood pressure, heart rate and respiration were studied in 15 cats on bilateral stimulation of rostral, middle and caudal regions of caudate nucleus. Hypotensive response was obtained on stimulation of anterior caudate nucleus, which changed to pressor response when posterior caudate nucleus was stimulated. Biphasic blood pressure responses were recorded on stimulation of middle caudatal area. No detectable changes were observed on heart rate and respiration. This suggests a role for caudate nucleus as a modulator in blood pressure regulation.


Subject(s)
Animals , Blood Pressure/physiology , Brain Chemistry , Cats , Caudate Nucleus/physiology , Coloring Agents , Electric Stimulation , Electrocardiography , Female , Ferrocyanides , Heart Rate/physiology , Male
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