ABSTRACT
<p><b>OBJECTIVE</b>To summarize the clinical experiences in the diagnosis and managements of hepatic veno-occlusive disease (HVOD).</p><p><b>METHODS</b>The clinical and pathologic data of 17 patients with hepatic veno-occlusive disease were analyzed retrospectively.</p><p><b>RESULTS</b>According to the results of imaging examination, clinical data and pathological data, 17 patients HVOD were divided into acute progressive HVOD and chronic HVOD. 2 cases out of the 11 acute progressive cases got improved, 2 cases died after medical treatment and 2 cases died after shunt operation. The 6 chronic HVOD, including 1 case with medical treatment and 5 cases with shunt operation, were cured.</p><p><b>CONCLUSION</b>Liver biopsy was an efficient method for the diagnosis of hepatic veno-occlusive disease. Acute progressive cases of hepatic veno-occlusive disease should be managed with medical treatment and the chronic cases could be treated with shunt surgery if medical treatment were inefficient.</p>