ABSTRACT
Objective To investigate the effect of ultrasound guided lumbar plexus sciatic nerve block anesthesia in elderly patients undergoing hip replacement.Methods From June 2015 to June 2016,84 elderly patients in Taizhou Bone Injury Hospital received hip replacement were randomly divided into 2 groups according to the digital table,with 42 patients in each group.The control group received epidural anesthesia ,the observation group received ultrasound guided lumbar plexus sciatic nerve block anesthesia .The occurrence of adverse reaction ,hemody-namic changes and the effect of anesthesia were observed in the two groups .Results In the control group,the SBP, DBP levels at T2,T3,T4,T5 were lower than those at T0 (t＝3.998,4.042,3.768,3.974,4.505,4.276,4.022, 4.076,all P＜0.05).In the observation group,the SBP,DBP levels at different time had no statistically significant changes(all P＞0.05).The SBP,DBP levels at T2,T3,T4,T5 in the observation group were higher than those in the control group (t＝3.667,3.839,3.997,3.654,3.330,3.675,3.759,3.885,all P＜0.05).The excellent and good rate of anesthesia effect in the observation group was 95.24%,which was significantly higher than 78.57% in the control group,and the difference was statistically significant (χ2＝12.209,P ＜0.05).Conclusion Ultrasound guided lumbar plexus sciatic nerve block anesthesia for elderly patients underwent hip replacement has good effect , and has no obvious influence on hemodynamics ,and with less adverse reactions.
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Objective To investigate the histological changes of normal human skin after fixed irradiation with multiple-pulse fractional Er:YAG laser.Methods After hair removal,the upper arms of 7 healthy volunteers were consecutively irradiated with multiple-pulse fractional Er:YAG laser.Tissue samples were resected from the irradiated skin at 1,24,48,72 hours,on day 5,7,15,and 30 after the irradiation.Hematoxylin and eosin(HE)staining and Masson staining were performed to observe the histological changes and collagen proliferation respectively.Immunohistochemical staining was used to detect the expression of heat shock protein(HSP)70 and 47.Results The consecutive irradiation with multi-pulse fractional Er:YAG laser generated an array of tapering microscopic treatment zones(MTZs)of gasification and ablation in the upper arm skin.After the irradiation,inflammation developed in the microscopic lesions with the epithelization of epidermal cells within 7 days; local dermal collagen was renewed and remodelled during the 7th to 30th day.HSP70 expression peaked as early as 48 hours after the treatment and maintained until the 7th day,while the high expression of HSP47 persisted from the 15th to 30th day after irradiation.Conclusion The fixed,multiplepulse and fractional Er:YAG laser irradiation can reach the deep dermis,and induce the local proliferation of dermal collagen.
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Object To study the change of serum soluble interleukin 2 receptor(SIL-2R) in syphilitic patients and its clinical significance.Methods The serum SIL-2R level in syphilitic patients of different stages and after therapy were detected using the ELISA technique.Results The serum SIL-2R level in syphiliti patients was higher than that in control group(P0 05).Conclusions SIL-2R level and its variation have some reference value for evaluating the therapeutic effect and judgement of the disease course in syphilitic patients.
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Objective To discuss the cause and preventive measure of positive stump in gastric cancer.Method The clinical data of 426 patients with residual cancer after resection of gastric cancer were retrospectively analyzed.Result In these cases 37(8.7%,37/426) were found to have residual cancers at the margin of resection.Conclusion The incidence of residual cancer at the cut edge is closely related to gross type,size of cancer,tumor stage and degree of differentiation.