Clinical efficacy of nasal cellulose powder for the treatment of allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the clinical efficacy of nasal cellulose powder for the treatment of allergic rhinitis.@*METHOD@#Thirty-six cases of patients with allergic rhinitis were randomly divided into control group and experimental group, 18 cases in each group. The control group was treated with physiological sea water and the experimental group with nasal fibrous powder. In 14, 28 days after drug evaluation in patients objective and subjective symptoms and signs improved nasal function (nasal airway resistance, the sense of smell) was compared.@*RESULT@#The experimental group and the control group of subjective symptoms and objective nasal function were improved, but the experimental group was significantly higher than that of control group, the difference was statistically significant (P<0.05); Two groups of patients had no adverse reaction occurred.@*CONCLUSION@#The clinical curative effect of Nasal cellulose powder used in the treatment of allergic rhinitis is distinct, without adverse reactions, and is conducive to improving patient stuffy nose, nasal itching, sneezing and other symptoms and improve the patients quality of life, is worth clinical use.

Analysis of related factors of tonsil postoperative pain / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To explore the related factors of tonsil postoperative pain.@*METHOD@#After founding databank a statistic analysis was performed on 90 cases with tonsillectomy who admitted in our hospital. Chi-square test were used to investigate the related factors for postoperative pain in those patients.@*RESULT@#After Chi-square test, the important effect factors in the postoperative pain were gender, age, surgical methods, preemptive analgesia, physical analgesia and preoperative anxiety level.@*CONCLUSION@#The pain after tonsillectomy is influenced by not only surgery itself, but also by preemptive analgesia, preoperative anxiety level and so on.

Clinical observation of functional endoscopic sinus surgery associated with radiofrequency ablation of inferior turbinate for chronic rhinosinusitis / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To explore the clinical efficacy of functional endoscopic sinus surgery (FESS) associated with radiofrequency ablation on chronic sinusitis.@*METHOD@#Fifty-four patients with chronic sinusitis were divided randomly into two groups: the study group and the control group, The study group received FESS associated with inferior turbinate lateral fracture and radiofrequency ablation treatment, while the control group received FESS associated with inferior turbinate lateral fracture treatment.@*RESULT@#The SNOT-20 score, Lund-Kennedy score, mucociliary clearance time and nasal airway resistance of the patients in the two groups after treatment were significantly improved than those before treatment (P < 0.05), and the sense of nasal congestion, headache and face pain, purulent rhinorrhea, postnasal drip, and other symptoms were also relieved. After treatment, the scores of SNOT-20 and the scores of Lund-Kennedy in the study group were significantly lower than those in the control group (P < 0.05), but no significant difference was found in mucociliary clearance time between the two groups after treatment.@*CONCLUSION@#FESS associated with radiofrequency ablation surgery is safe and effective for chronic sinusitis.

Effects of sleeping body posture on sleeping structure and respiratory events in patients with OSAHS / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To observe the effects of sleeping body posture on sleeping structure and respiratory events in patients with OSAHS.@*METHOD@#We assessed the sleeping body position, the sleeping structure, position specific AHI and the Epworth Sleepiness Scale (ESS) in a total of 80 patients with Positional OSAHS. The patients were grouped according to AHI: mild OSAHS (5 or = 30). The polysomnography data and clinical characteristics were compared between each group.@*RESULT@#The severe OSAHS group, when compared with the mild and the moderate ones, had a significant different in REM%, NREM%, NREM LSaO2, RDI, S-AHI and L-AHI due to posture (P 0.05). For mild-to-moderate groups, there was no correlation between the ESS and the AHI for any position different (P > 0.05). For severe group, the ESS was significantly correlated with L-AHI (r = 0.551; P < 0.01); the REM L-AHI and NREM L-AHI was also significantly correlated with ESS of severe group (r were 0.516 and 0.528, P < 0.01).@*CONCLUSION@#The L-AHI, NREM L-AHI, REM L-AHI and NREM LSaO2 were considered to monitor the stability of OS-AHS, while REM LSaO2 were consider to clarify the severity of OSAHS.

Effects of bupivacaine versus lidocaine infiltration on postoperative analgesia in pediatric tonsillectomy patients / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To compare the effects of bupivacaine, lidocaine and saline injections in alleviating post tonsillectomy pain.@*METHOD@#We recruited 60 patients into the study. All subjects were randomly allocated into 3 groups. Group 1 received 0.9% sodium chloride (saline group), group 2 received 0.25% bupivacaine (bupivacaine group) and group 3 received 2% lidocaine (lidocaine group), infiltrated around each tonsil. Pain was evaluated with McGrath's face scale.@*RESULT@#The postoperative pain scores at 2 and 6 hours were similar among the groups (P>0.05). The pain scores in the bupivacaine group were lower than those in the saline group at 12 h (P 0.05).@*CONCLUSION@#Local infiltration of bupivacaine is a relatively and safe effective method and is equivalent to use of lidocaine for post tonsillectomy pain.

Comparison of application of several psychophysical olfactory test methods in clinic / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To compare the consistency of four olfactory psychophysical test methods.@*METHOD@#Twenty out-patients were done with olfactory psychophysical test and the results were analyzed. The four olfactory psychophysical test methods include simple test method, UPSIT, Sniffin Sticks test and the T&T olfactometer test.@*RESULT@#The consistency of four test methods reached 85%, and UPSIT test can identify pseudo smell obstacles.@*CONCLUSION@#There is reliable and stable outcome of the four psychophysical olfactory test methods.

The serum level transformation of IFN-gamma, IL-4 and IgE before and after SIT in patients with allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To assess the efficacy and the transformation of IFN-gamma, IL-4, total IgE and specific IgE before and after specific immune therapy(SIT) in patients with allergic rhinitis.@*METHOD@#The subjective symptom and levels of IFN-gamma, IL-4, total IgE and specific IgE were observed in 40 patients with allergic rhinitis before and after SIT.@*RESULT@#Total effective rate in patients after SIT was 85%. There's no significant difference between the levels of specific IgE before and after SIT(P>0.05) ,while the levels of IL-4 and total IgE were significantly lower, the levels of IFN-gamma were significantly higher pre than that of post SIT.@*CONCLUSION@#SIT is safe and effective,and can regulate the levels of IFN-gamma, IgE and IL-4. But the role of specific IgE in SIT is still unknown.

The effect of middle ear effusion on enzymatic digestion of DNA in middle ear effusions of chronic otitis media with effusion / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To determine whether or not the bacterial DNA which was detected by PCR comes from viable bacteria.@*METHOD@#Observing the affection of middle ear effusion (MEE) on DNA viscosity and enzymatic digestion of DNA.@*RESULT@#The middle ear effusion and DNA are stable and DNase 1 rapidly digests DNA. The effusion does not seem to degrade DNA. The middle ear effusion signficantly inhibits DNase 1.@*CONCLUSION@#Middle ear effusion provides an inhibition of the enzymatic digestion of purified DNA. Thus any DNA found in effusion by PCR techniques could well be fossilized remains and chronic otitis media with effusion may not be the bacterial infection.

The effect of plasma radiofrequency ablation on nasal mucosa provocative tests for allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#In order to explore the effect of plasma radiofrequency ablation on nasal mucosa provocative tests for allergic rhinitis.@*METHOD@#Eighty patients with allergic rhinitis were enrolled in this study. The nasal mucosa provocative tests and nasal airway resistance and subjective nasal patency feeling were studied before and after plasma radiofrequency ablation treatment. The correlation of subjective and objective nasal patency was evaluated.@*RESULT@#The preoperative nasal mucosa provocative test of all the patients allergic to mites were positive. The nasal mucosa provocative tests were negative within 72 patients, while remained positive in eight patients after 3 months of operation. The nasal airway resistance decreased from (0.772 +/- 0.224) kPa x s/L to (0.221 +/- 0.112) kPa x s/L after surgery (P < 0.01); Visual analog scale decreased from 7.0 +/- 2.0 to 2.5 +/- 1.5 after 3 months of operation (P < 0.01).@*CONCLUSION@#Due to its ability to reduce the sensitivity of the nasal mucosa, nasal airway resistance and improve subjective feeling of nasal patency, plasma radiofrequency ablation is effective for the treatment of patients with allergic rhinitis.

The effect of adenoidectomy in different operative methods on the function of eustachian tube / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To compare the effect of two different approaches in curettage of adenoid hypertrophy on eustachian tube function: the endoscopic assisted transoral adenoidectomy, and the traditional transoral curette adenoidectomy.@*METHOD@#Clinical data of adenoid hypertrophy patients who underwent surgery therapy were prospectively analyzed; Eustachian tube function were compared among them.@*RESULT@#Both traditional curettage of adenoids through mouth(group TCA) and endoscopic assisted transoral adenoidectomy (group ETA) significantly improved eustachian tube function (P < 0.01), while group ETA seemed to have a better outcomes (P < 0.01).@*CONCLUSION@#Both traditional curettage of adenoids through mouth and the endoscopic assisted transoral adenoidectomy can significantly improve eustachian tube function, and the endoscopic assisted transoral adenoidectomy produces a better outcome.

The correlative study between skin prick test with antigens and nasal provoking test in patients with allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To study the distribution of allergens in our district and the correlation between skin prick test with antigen and nasal provoking test in patients with allergic rhinitis.@*METHOD@#A total of 1400 cases with allergic symptoms and signs underwent skin prick test with standardized aero antigens provoking by Allergo Phamar Company. The patients allergic to Dermatophagoides with different scale of the skin prick test were taken nasal provoking test in order to evaluate the correlation between skin prick test and nasal provoking test.@*RESULT@#One thousand and eighty-eight (78%) cases showed a positive result in skin prick test. The percent of patients with positive skin prick test were as follows: 462 cases of Dermatophagoides pteronyssinus, 428 cases of Dermatophagoides farinae. Positive perennial aero antigens were 52.2% (568), positive seasonal aero antigens were 35.7% (388). All the patients of the scale of skin prick test was +++ and ++++ were positive. There are 29 patients were positive with nasal provoking test which the scale of skin prick test was ++. There are 21 patients were positive with nasal provoking test, which the scale of skin prick test was +.@*CONCLUSION@#The correlation between skin test with antigens and nasal provoking test in patients whose positive scale were +++ and ++++. There are false positive in the patients whose positive scale were + and ++. The specific immunotherapy should consider the scale of the skin prick test and eliminate the false positive before the therapy.

The correlative study between skin prick test with antigens and nasal provoking test in patients with allergic rhinitis / 临床耳鼻咽喉头颈外科杂志

Objective:To study the distribution of allergens in our district and the correlation between skin prick test with antigen and nasal provoking test in patients with allergic rhinitis.Method:A total of 1 400 cases with allergic symptoms and signs underwent skin prick test with standardized aeroantigens provoking by AllergoPhamar Company. The patients allergic to Dermatophagoides with different scale of the skin prick test were taken nasal provoking test in order to evaluate the correlation between skin prick test and nasal provoking test.Result:One thousand and eighty-eight(78%) cases showed a positive result in skin prick test.The percent of patients with positive skin prick test were as follows: 462 cases of Dermatophagoides pleronyssinus, 428 cases of Dermatophagoides farinae. Positive perennial aeroantigens were 52.2%(568),positive seasonal aeroantigens were 35.7%(388). All the patients of the scale of skin prick test was +++ and ++++ were positive. There are 29 patients were positive with nasal provoking test which the scale of skin prick test was ++. There are 21 patients were positive with nasal provoking test,which the scale of skin prick test was +.Conclusion:The correlation between skin test with antigens and nasal provoking test in patients whose positive scale were +++ and ++++. There are false positive in the patients whose positive scale were + and ++. The specific immunotherapy should consider the scale of the skin prick test and eliminate the false positive before the therpy.

Postlabyrinthine approach of cerebellopontine angle surgery via endoscope / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To estimate the value of endoscope on postlabyrinthine approach of cerebellopontine angle surgery.@*METHOD@#Transpostlabyrinthine endoscopic excision of glossopharyngeal nerve to treat 2 glossopharyngeal neuralgia patients. Observe the endoscopic eyespot and estimate the appliance and virtue of the surgery.@*RESULT@#The two patients both have satisfied outcomes and remained free of disease after surgical treatment. We got a wide eyespot from trigeminal to vagus nerve. The internal acoustic porous is a fixed structure of the cerebellopontine angle and it is also a perfect landmark during the surgery.@*CONCLUSION@#Endoscopic postlabyrinthine approach provides a shorter path to cerebellopontine angle and endoscope provides a unique way to explore the cerebellopontine angle and to identify the exact location of the pathological changes, including a multipoint of view. Complicated and skilled operation restricts the surgery.

Distribution of nasal airway resistance in normal and pathologic nasal cavity / 中国耳鼻咽喉头颈外科

OBJECTIVE In order to explore the site of the nasal valve.METHODS The distribution of nasal airway resistance were studied in normal adults, and patients with chronic rhinitis,patients underwent partial inferior turbinectomy,patients with the deviation of nasal septum and the patients underwent correction of the nasal septum.RESULTS Before the nasal mucosa decongested,the site of the most effect on the NAR was located in pyriform fossa in normal adults. After the nasal mucosa decongested,the site of the most effect on the NAR was located in the ostium internum.The most significantly site which effect on the NAR were pyriform fossa and the ostium internum before and after operation in the patients who suffer from chronic rhinitis.The site of the most effect on the NAR was in the place of deviation of the nasal septum before operation and in the pyriform fossa after operation.CONCLUTION The result suggested that the site of the nasal valve is changeable and related to the condition of contraction and relaxation of the nasal mucosa and the extent of nasal patency.

The Study of DNA in Middle Ear Effusions / 中国医师杂志

Objective To determine whether or not the bacterial DNA which was detected by PCR comes from viable bacteria.Methods Observe the effection of middle ear effusion(MEE) on DNA viscosity and enzymatic digestion of DNA.Results The middle ear effusion and DNA are stable and DNase 1 rapidly digests DNA,The effusion does not seem to degrade DNA.The middle ear effusion signifcantly inhibits DNase 1.Conclusions Middle ear effusion provides an inhibition of the enzymatic digestion of purified DNA.Thus any DNA found in effusion by PCR techniques could well be fossilized remains and chronic otitis media with effusion may not be the bacterial infection that recent studies have suggested.