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Braz. j. infect. dis ; Braz. j. infect. dis;12(6): 555-557, Dec. 2008. ilus
Article in English | LILACS | ID: lil-507465

ABSTRACT

Meningitis is a common evolution in progressive disseminated histoplasmosis in children, and is asymptomatic in many cases. In leukemia, the impaired of the T cells function can predispose to the disseminated form. The attributed mortality rate in this case is 20 percent-40 percent and the relapse rate is as high as 50 percent; therefore, prolonged treatment may be emphasized. We have described a child with acute myeloid leukemia (AML), that developed skin lesions and asymptomatic chronic meningitis, with a good evolution after prolonged treatment with amphotericin B deoxycholate followed by fluconazole.


Subject(s)
Adolescent , Humans , Male , Histoplasmosis/diagnosis , Leukemia, Myeloid/immunology , Meningitis, Fungal/diagnosis , Acute Disease , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Chronic Disease , Drug Combinations , Drug Therapy, Combination , Deoxycholic Acid/therapeutic use , Fluconazole/therapeutic use , Histoplasmosis/drug therapy , Immunocompromised Host , Leukemia, Myeloid/microbiology , Meningitis, Fungal/drug therapy , Meningitis, Fungal/microbiology , Treatment Outcome
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