Functional Near-Infrared Spectroscopy as a Personalized Digital Healthcare Tool for Brain Monitoring

The sustained growth of digital healthcare in the field of neurology relies on portable and cost-effective brain monitoring tools that can accurately monitor brain function in real time. Functional near-infrared spectroscopy (fNIRS) is one such tool that has become popular among researchers and clinicians as a practical alternative to functional magnetic resonance imaging, and as a complementary tool to modalities such as electroencephalography. This review covers the contribution of fNIRS to the personalized goals of digital healthcare in neurology by identifying two major trends that drive current fNIRS research. The first major trend is multimodal monitoring using fNIRS, which allows clinicians to access more data that will help them to understand the interconnection between the cerebral hemodynamics and other physiological phenomena in patients. This allows clinicians to make an overall assessment of physical health to obtain a more-detailed and individualized diagnosis. The second major trend is that fNIRS research is being conducted with naturalistic experimental paradigms that involve multisensory stimulation in familiar settings. Cerebral monitoring of multisensory stimulation during dynamic activities or within virtual reality helps to understand the complex brain activities that occur in everyday life. Finally, the scope of future fNIRS studies is discussed to facilitate more-accurate assessments of brain activation and the wider clinical acceptance of fNIRS as a medical device for digital healthcare.

Application of Near-Infrared Spectroscopy in Neurological Disorders: Especially in Orthostatic Intolerance

Near-infrared spectroscopy (NIRS), a noninvasive optical method, utilizes the characteristic absorption spectra of hemoglobin in the near-infrared range to provide information on cerebral hemodynamic changes in various clinical situations. NIRS monitoring have been used mainly to detect reduced perfusion of the brain during orthostatic stress for three common forms of orthostatic intolerance (OI); orthostatic hypotension, neurally mediated syncope, and postural orthostatic tachycardia syndrome. Autonomic function testing is an important diagnostic test to assess their autonomic nervous systems for patients with symptom of OI. However, these techniques cannot measure dynamic changes in cerebral blood flow. There are many experimentations about study of NIRS to reveal the pathophysiology of patients with OI. Research using NIRS in other neurologic diseases (stroke, epilepsy and migraine) are ongoing. NIRS have been experimentally used in all stages of stroke and may complement the established diagnostic and monitoring tools. NIRS also provide pathophysiological approach during rehabilitation and secondary prevention of stroke. The hemodynamic response to seizure has long been a topic for discussion in association with the neuronal damage resulting from convulsion. One critical issue when unpredictable events are to be detected is how continuous NIRS data are analyzed. Besides, NIRS studies targeting pathophysiological aspects of migraine may contribute to a deeper understanding of mechanisms relating to aura of migraine. NIRS monitoring may play an important role to trend regional hemodynamic distribution of flow in real time and also highlights the pathophysiology and management of not only patients with OI symptoms but also those with various neurologic diseases.

Extraccion de cuerpos extranos (cateteres) de la auricula derecha u aorta abdominal por via percutanea: informe de dos casos y revision de la literatura / Extraction of foreign bodies (catheters) from the right atrium and abdominal aorta by percutaneos way: report of 2 cases and review of the literature

Se presentan dos casos de emvolizacion de cuerpos extranos (cateteres) y su extraccion con tecnicas modificadas. En el primero de los casos, el cuerpo extrano estaba ubicado en las cavidades derechas del corazon y se logro su captura mediante una tecnica modificada que utiliza in cateter Pigtail y un bioptomo introducidos secuencialmente por via percutanea. En el segundo de los casos, el cuerpo extrano estaba localizado en la aorta abdominal y se logro su extraccion por via percutanea con la ayuda de un cateter Fogarty. Se revisa la literatura sobre el tema y dada la frecuencia cada vez mayor del uso de cateteres intravasculares, se dan recomendaciones para evitar este tipo de complicación