Peripheral Giant Cell Granuloma: A Case Report and Review of Literature.

Peripheral Giant Cell Granuloma or so called “Giant cell epulis” is the most common oral giant cell lesion.It usually presents as a purplish-red soft tissue nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. This lesion probably does not represent a true neoplasm but it may be a reactive in nature which is believed to be stimulated by local irritation or trauma, but the cause is not known with certainty. A case of peripheral giant cell granuloma arising at the left maxillary premolar region in a 18 year old boy is being reported here. The lesion was completely excised upto the periosteum level; there was no residual or recurrence of swelling or bony defect apparent in the area of biopsy after a follow-up period of 1 year.

Surgical Stabilization of Pelvic and Acetabular Fractures: A Review on the Determinants of Clinical Outcomes

Aim: Pelvic and acetabular fractures are associated with high energy trauma. The aim of this study was to identify factors that are associated with specific clinical outcomes following treatment for these fractures. Methods: A consecutive series of 30 patients who had surgical intervention for either pelvic or acetabular fractures formed the sample for this study. Clinical variables reviewed were: age, associated injuries, number of surgical procedures, time to surgery and post operative complications. Cli

Seasonal variation in the incidence of hyponatremia.

AIM: To study the seasonal variation in the incidence of hyponatremia and to correlate it with the rainfall pattern. METHOD: Retrospective analysis of patients having serum sodium of less than 120 meq/L was done during the 24 months from March, 1995. Patients with fever, renal failure, cardiac failure, cirrhosis, hyperlipidemia, hyperproteinemia, patients taking diuretics and postoperative patients were also excluded. Average inpatient number and rainfall for each month was noted. Daily incidence of hyponatremia was expressed as percentage of total inpatients for each day and was compared with the rainfall. RESULTS: A total of 353 patients had hyponatremia during the two years from March, 1995; 174 cases during the first year and 179 during the second year. Average inpatient strength was 302.17 +/- 21.41 during the first year and 313.67 +/- 12.94 during the next year. The incidence of hyponatremia was 0.24 +/- 0.096% between June and August and 0.1 +/- 0.04% between December and February (95% confidence interval 0.045-0.235, p < 0.01). Statistically significant correlation was observed between rainfall pattern and hyponatremia, r = 0.711, 95% confidence interval 0.478-0.913, p = 0.01 during 95-96 and r = 0.825, 95% confidence interval 0.478-0.949, p < 0.001, during 96-97. CONCLUSION: Incidence of hyponatremia is higher during the peak southwest monsoon season with similar pattern for the study period of two years. Humidity and temperature may have important role in the manifestation of hyponatremia.

Influence of smoking and hypertension on left ventricular mass.

OBJECTIVE: The present study was designed to observe the influence of smoking and hypertension on left ventricular mass (LVM), both individual and the combined effect. METHODS: This study was conducted in the Department of Medicine, SMS Medical College Hospital, Jaipur. Hundred patients were included in the study. They were divided into four groups--non smoker normotensives, non-smoker hypertensives, smoker normotensives and smoker hypertensives. They were also divided into smokers and nonsmokers and hypertensives and normotensive. Patients of age group 31-65 years of both sexes were chosen. Patients with secondary hypertension, diabetes mellitus, dyslipidemia, cardiomyopathies, valvular heart disease women on oral contraceptives were excluded from the study on the basis of history and relevant laboratory tests. An M-mode echocardiography was done and the LV mass was calculated by the formula proposed by Devereux et al. LV mass = 0.8 [1.04 (IVSd + LVIDd + LVPWd)3 - (LVIDd)3] + 0.6 gms RESULTS: The mean LV mass (in gms) in the four groups of nonsmoker normotensives, nonsmoker hypertensives, smoker normotensives and smoker hypertensives are 106.77 +/- 25.78, 165.3 +/- 42.55, 154.53 +/- 24.6 and 228.78 +/- 56.88 respectively. The comparison of mean LV mass (in gms) of smokers and nonsmokers were 191.66 +/- 40.74 and 136.04 +/- 36.16 (P < 0.001) respectively. The comparison of the mean LV mass (in gms) of hypertensives and nonhypertensives were 197.25 +/- 49.72 and 126.29 +/- 25.19 (P < 0.001) respectively. Comparison of the mean LV mass (in gms) of patient with two risk factors i.e., smokers hypertensives with patients without any risk factor i.e., nonsmoker normotensive were 228.78 +/- 56.88 and 106.77 +/- 25.78 (P < 0.001) respectively. While comparison of the mean LV mass (in gms) of patients with one risk factor each i.e., smoker normotensives and nonsmoker hypertensives were 165.3 +/- 42.55 and 154.53 +/- 24.6 (P < 0.05) respectively. CONCLUSION: Both smoking and hypertension cause an increase in LV mass, hypertension causing a more increase, than smoking, individually. Both smoking and hypertension combine together to increase the LV mass, more than either of them individually. Smoking by itself can cause an increase in LV mass independent of hypertension.

Microbiological study of urethritis in men attending a STD clinic.

A microbiological study of 275 male patients suffering from urethritis and 100 healthy male controls showed that Neisseria gonorrhoeae (130), Ureaplasma urealyticum (81), Staphylococcus aureus (38), and alpha and beta streptococci (34) were the common isolates. Specificity and sensitivity of the direct fluorescent antibody technique in the detection of N. gonorrhoeae in 130 urethral samples, were found to be 100 per cent. Penicillin (10 units/disc) resistance was found in 36.93 per cent of N. gonorrhoeae. Minimum inhibitory concentration of penicillin for 75 isolates of N. gonorrhoeae (including 5 beta lactamase producers) varied from 0.01-5 micrograms/ml with a 95 per cent confidence limit range of 0.26-0.61 microgram/ml. Most of the N. gonorrhoeae isolates tested were sensitive to norfloxacin and spectinomycin. Inclusion bodies of Chlamydia trachomatis were observed in 25 patients.

Chondroid syringoma-scalp. A case report.

A case of chondroid syringoma of scalp is reported. The case is of particular interest because of repeated recurrence with bone and dural infiltration.

Uniocular proptosis in children.

A retrospective study on 80 children with uniocular proptosis has been done. Of these 57 had orbital lesions, 19 had periorbital lesions and 4 had intracranial lesions. The clinical, radiological and pathological aspects as well as the management of these conditions are discussed.