ABSTRACT
<p><b>AIM</b>To study the active constituents of Swertia davidi Franch.</p><p><b>METHODS</b>Chemical components were isolated by column chromatography and their structures were established mainly by spectroscopic means (UV, IR, NMR, 2D-NMR, MS).</p><p><b>RESULTS</b>Three substances were identified as 2,5-dimethoxyl-1, 4-dicarboxyl benzene (VIII), 1,5,8-trihydroxyl-3,4-dimethoxyl xanthone (IX) and 1,8-dihydroxyl-3-(3'-hydroxyl-butoxy) xanthone (X).</p><p><b>CONCLUSION</b>Compounds VIII and IX were isolated from Swertia davidi Franch, for the first time, whereas compound X is a new xanthone, named daviditin B with antioxygenated activity in vitro.</p>
Subject(s)
Antioxidants , Chemistry , Molecular Conformation , Molecular Structure , Plants, Medicinal , Chemistry , Swertia , Chemistry , Xanthones , ChemistryABSTRACT
<p><b>AIM</b>To study the active constituents of Swertia davidi Franch..</p><p><b>METHODS</b>Chromatography was used to isolate and purify the chemical components, their structures were identified by spectral analysis.</p><p><b>RESULTS</b>Three compounds were identified as 1,7-dihydroxy-3,8-dimethoxyxanthone (gentiacaulein) (V), 1,8-dihydroxy-3,7-dimethoxyxanthone (methylswertianin) (VI) and 1,8-dihydroxy-3,4,7-trimethoxyxanthone (VII).</p><p><b>CONCLUSION</b>Compound VII is a novel xanthone, named daviditin A, the others were isolated from Swertia davidi Franch. for the first time.</p>