ABSTRACT
Natural products continue to play an important role in the discovery and development of new pharmaceuticals. Several chemical compounds have been extracted and identified from its species known as Lantana camara (L .camara). The present study was designed for phytochemical analysis of L. camara and extraction of bioactive compound by HPLC. This also included the antimicrobial activity of the bio active compound obtained by crude extract and the column extract. The study showed the presence of the bioactive component parthenin extracted from the HPLC analysis at a peak height of 10.3807 and it was showing antimicrobial activity against E. coli, P. aeruginosa, B. subtilis and E. fecalis, crude (6.8 to 8.1 mm ) and column (4.0 to 6.2 mm) zone of inhibition.