ABSTRACT
Liddle's syndrome is a classical entity which rarely presents with secondaryhypertension. Work up for this entity is necessary while dealing with cases ofhypertension, because the treatment protocol is different. We report a case of a 35-year-old male, who presented to us with history of recurrent headaches andfatiguability. Examination revealed hypertension and hypokalaemia. No one in familywas hypertensive. After work up, he was diagnosed to have Liddle’s syndrome.Liddle's syndrome is inherited as an autosomal dominant condition. It ischaracterized by increased sodium reabsorption and potassium secretion bykidneys.[1-3] The classic triad of presentation is hypertension, hypokalaemia, andmetabolic alkalosis, which often resembles hyperaldosteronism.[4] It usually affectsyounger age group,, but rarely it may be diagnosed in adulthood.[5]Secondary hypertension may be the first presentation in Liddle’s syndrome.Diagnosis of this syndrome is important because the treatment is different from thatof other causes of secondary hypertension. The triad of hypertension, hypokalaemiaand metabolic alkalosis is usually seen in Liddle’s syndrome.