ABSTRACT
The carcinosarcoma (malignant mixed mullerian tumour) of uterus is an aggressive neoplasm composing of malignant glands in the malignant stroma showing biphasic appearance. A 55 year old woman presented with discharge per vaginum of one month duration. Earlier she was given radiotherapy for squamous cell carcinoma of vulva, six years back. Abdominal examination was insignificant. USG suggested presence of post-radiation effect with uterine mass. Panhysterectomy was done and on histopathology, the diagnosis of carcinosarcoma (heterologous variant) was made. The case is being reported and discussed.
Subject(s)
Carcinoma, Squamous Cell/radiotherapy , Carcinosarcoma/diagnosis , Female , Humans , Middle Aged , Mixed Tumor, Mullerian/diagnosis , Neoplasms, Radiation-Induced/diagnosis , Neoplasms, Second Primary/diagnosis , Uterine Neoplasms/diagnosis , Vulvar Neoplasms/radiotherapyABSTRACT
We present a case of a 28-year-old male weight lifter who died suddenly while driving a bicycle. Forensic autopsy and histopathological examinations revealed granulomatous lesions in the myocardium and hilar lymph nodes. The latter had massive caseation necrosis, epithelioid granulomas and Langhans' giant cells suggestive of tuberculosis. However, the myocardium showed predominantly multinucleated foreign body and myogenic giant cells, lymphocytes, plasma cells, macrophages, eosinophils. Staining for acid-fast bacilli was negative. The present case highlights the difficulty in establishing whether the granulomatous lesions in the hilar lymph nodes and the myocardium are incidental findings or whether they are related by the same pathogenetic mechanisms.
Subject(s)
Adult , Autopsy , Cardiomyopathies/complications , Death, Sudden/etiology , Granuloma, Giant Cell/complications , Humans , Male , Myocarditis/complicationsABSTRACT
A rare case of plasma cell leukaemia and papillary serous cystadenacarcinoma of ovary in a 58-year-old female is reported.