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Indian J Exp Biol ; 2001 Apr; 39(4): 378-80
Article in English | IMSEAR | ID: sea-56639

ABSTRACT

Anxiety disorders are more prevalent not only in normal individuals but also in diabetes mellitus. Diazepam, a benzodiazepine, and buspirone, an azaspirodecanedione, are the most often prescribed anxiolytics. Present study was aimed to investigate the effect of diazepam and buspirone on the blood sugar levels in rabbits. Buspirone (0.5 mg/kg/day p.o.) and diazepam (0.6 mg/kg/day p.o.) did not affect the glucose levels in rabbits even after one month of treatment. Present findings suggest that these two anxiolytics have minimal effect on blood sugar control.


Subject(s)
Animals , Anti-Anxiety Agents/administration & dosage , Anxiety Disorders/complications , Blood Glucose/metabolism , Buspirone/administration & dosage , Diabetes Complications , Diabetes Mellitus/blood , Diazepam/administration & dosage , Female , Humans , Male , Rabbits
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