ABSTRACT
This study was conducted to assess the presence of various types of cardiac lesions in pregnant females admitted to a tertiary care hospital of Punjab. 97 women having pregnancy and heart disease were assessed for the various etiologies, cardiac lesions, maternal and perinatal outcomes. Rheumatic heart disease (RHD) with isolated mitral stenosis was the commonest acquired lesion while mitral valve prolapse was the predominant lesion among the congenital heart disease. In the miscellaneous group, cardiomyopathy was the leading cause. Multiple cardiac lesions were diagnosed in 36 women. Majority delivered by caesarean section and some had spontaneous vaginal delivery while few required induction of labour. 19 women had cardiac complications. There were three maternal deaths.This study concluded that rheumatic heart disease in pregnancy is still predominant though acquired cardiac lesions are rising. A careful observation and management during pregnancy can improve the maternal & fetal outcomes.
ABSTRACT
To evaluate diagnostic value of PCR (Polymerase chain reaction) in female genital tuberculosis and to study conception rate after ATT (Anti tubercular treatment) in positive cases. Sixty infertile patients were investigated for presence of Mycobacterium tuberculosis (MTB) by PCR of endometrial curettings. PCR demonstrated MTB DNA in 28 patients. ATT was started in diagnosed cases which were followed up for two years for conception.All patients with laparoscopy suggestive of tuberculosis, more than 50% of those with a probable diagnosis and significant number of those with incidental findings were positive by PCR. Six PCR positive cases conceived within two years after taking ATT for 9 months. Four patients conceived spontaneously and two patients with intrauterine insemination. PCR offered increased sensitivity in determining tuberculosis etiology in female infertility and significant number of patients conceived after regular ATT.