Prevalence and Patterns of Self-Medication Practices In Urban Field Practice Area, Dharwad

Background: The estimated prevalence of self-medication practices globally and nationally are 95% and 71% respectively. Inappropriate self-medication leads to irrational use of drugs and development of drug resistance. Hence, the present study was conducted to estimate the prevalence and patterns of self-medication practices in urban field practice area, SDMCMS&H, Dharwad. Methods: A cross-sectional study was conducted during 2018-2019 among adult aged 18-60 years. The estimated sample size was 335. Systematic random sampling technique was used to select the samples. Data was collected by administering questionnaire to the consented study participants. Results: A total of 335 adults participated in our study. The prevalence of self-medication practices was 46%. Minor-illness 89(57.7%) and quick relief 50(32.46%) were the major reasons given for practicing self-medication. Fever and headache 146(94.8%) was the most common symptom and analgesic 128(83.11%) was the most common drug used. significant association was found between self-medication practices and religion, age, employment and presence of health care workers in the family. Conclusion: Around half of the study participants practiced self-medication. Easy availability and limited knowledge are the reasons for wide range of practice. Creating awareness about dangers of self-medication is important to prevent untoward effects and drug resistance.

Limitations of Conventional Parameters and Role of Urinary Protein Biomarkers in the Determination of Drug Induced Acute Kidney Injury in Very Early Stage.

Drug-induced Acute Kidney Injury (AKI) constitutes an important cause of acute renal failure and chronic kidney disease in present day clinical practice. Drug-induced acute renal failure (ARF) accounted for 20% of all ARF in an Indian study. The incidence and prevalence of chronic kidney disease (CKD) has dramatically increasing worldwide. Progression of AKI from mild or moderate to end stage may be prevented by selecting potentially effective therapies, if it is detected in very early stage. But early detection of AKI is often difficult due to paucity of early predictive noninvasive biomarkers. Development of omics technology has led to the identification of several urinary protein biomarkers and transcriptional biomarkers, which enable earlier detection of kidney injury. Urinary protein biomarkers have great benefit due to the easy or non-invasive availability of urine and many showing good predictive power. Several urinary protein biomarkers have been identified and have demonstrated superiority in detecting kidney injury in comparison to conventional parameters like serum creatinine (SCr), blood urea nitrogen (BUN) etc. These promising experimental biomarker of kidney damage require further confirmation of its use in routine clinical use.

Re-evaluation of uterine packing for postpartum haemorrhage

A retrospective study was conducted at the Department of Obstetrics and Gynaecology [Unit II], Liaquat Medical College Hospital, Jamshoro, Hyderabad, with the objective of determining the use of uterine packing for control of postpartum haemorrhage [PPH] and to evaluate the efficacy and complications of the procedure. Data was collected from the obstetric records of all the deliveries over a period of five years, from January 1992 to December 1996. All women who had undergone uterine packing for control of postpartum haemorrhage were identified and indications and postoperative complications analysed

Obstetric hysterectomy

A review of 83 cases of obstetric hysterectomy performed at Liaquat Medical College Hospital over a period of 30 months from January 1992 to June 1994. During same period 9685 deliveries were conducted, giving an incidence of 1 obstetric hysterectomy per 116 deliveries. The most common indication for obstetric hysterectomy was uterine rupture 42[17%], leiomyoma 2[2.4%] and established uterine infection 6[7.2%]. In 62% of hysterectomies performed for uterine rupture, the etiological factors appeared to be obstructed labour or oxytocin augmentation. In 48% of hysterectomies performed for placenta accrela there were one or more previous Caesarean sections

analysis of maternal deaths in hospital in Hyderabad

During the 6-year period from 1990 to 1995 maternal deaths which occurred in Unit I and Unit II of the Department of Obstetric and Gynaecology, Liaquat Medical College and Hospital, Hyderabad were analysed in depth. During the period of study were 268 maternal deaths, 12.940 deliveries and 11.542 live births. Thus, the maternal mortality ratio was 23.12/1000 live births [20.71/1000 total births]. The main cause of maternal deaths was sepsis followed by eclampsia. When compared to the study carried out during 1986-1990 in the same institution there appears to be no significant change in the trend of maternal mortality. This reflects that the socio-economic and health care services are still grossly inadequate in quality and quantity

Advanced germ cell tumour of ovary in pregnancy

A case of advanced germ cell tumour of ovary [dysgerminoma] in pregnancy is being described. The entity is usually difficult to diagnose. Utilizing conservative surgical procedures in young females in the early stages of the disease, fertility can be conserved