Application of natural orifice transluminal endoscopic surgery in pelvic floor dysfunction / 中国实用妇科与产科杂志

In recent years,due to the coming of aging society,pelvic floor dysfunction(PFD)has gradually become one of the research hotspots in the field of obstetrics and gynecology worldwide.At present,surgery is the preferred treatment for moderate to severe PFD patients. With the development of minimally invasive surgery technology and the renewal of minimally invasive concept,PFD treatment options have been improved continuously. Natural orifice transluminal endoscopic surgery has been applied to gynecological surgery because of its fast recovery,slight pain and being without abdominal incision. Although the development of minimally invasive surgery provides more surgical options,different surgical methods have their advantages and disadvantages,and they should be controlled.Therefore,the age,symptoms,signs,medical history and general condition of the patients should be comprehensively evaluated to achieve the best therapeutic effect.

Curative effect of paclitaxel and cisplatin combined chemotherapy on cervical cancer and its relation with tissue micro vascular and lymphatic vessels density

This study was to discuss the curative effect of paclitaxel and cisplatin combined chemotherapy on cerical%miner and its relation with tissue micro vascular and lymphatic vessels density. The combined chemotherapy of paclitaxel 135mg/m2 and cisplatin 25mg/m2 were taken to observe the clinical curative effect. The postoperative paraffin tissue had been collected, had performed the LYVE-1 [lymphatic endothelium specific hyaluronan receptor-1] and CD31 immunohistochemical staining. The complete remission rate of high micro lymphatic vessels density group [was or more 6.0] and high micro vascular density group were obviously higher than in low micro lymphatic vessels density group and low micro vascular density group, the difference was statistically significance [P<0.05]. This study further analyzed the relation of MVD and LVD with clinical pathological parameters. The difference was statistically significant [P<0.01]. The curative effect of paclitaxel and cisplatin combined therapy was promising, positive and was closely related with cervical cancer tissue LVD and MVD. The LVD and MVD could be one of the predictors of early cervical CIN and early cervical cancer development