ABSTRACT
Objective To investigate the effect of brain natriuretic peptide (BNP) ,uric acid (UA) ,lactic dehydrogenase(LDH) and troponin T (TnT)in the diagnosis and prognosis observation of cardiovascular disease .Methods A total of 271 cases of cardio-vascular diseases and 271 cases of non-cardiovascular diseases were selected as the cardiovascular diseases group and control group respectively ,moreover the cardiovascular diseases group was further divided into the Uyghur cardiovascular diseases group and Han cardiovascular diseases group according to the nationality type .The levels of BNP ,LDH ,UA and TnT were detected in all cases . Then the detection results were statistically analyzed .Results The levels of BNP ,UA ,LDH and TnT in the cardiovascular diseases group were significantly higher than those in the control group ,the difference was statistically significant (P<0 .05);the LDH and TnT levels in the Uyghur cardiovascular diseases group were higher than those in the Han cardiovascular diseases group ,while the BNP and UA levels in the Han cardiovascular diseases group were higher than those in the Uyghur cardiovascular diseases group , the difference was not statistically significant (P>0 .05);the decrease after 1 week treatment in the patients with heart failure and coronary heart disease was most significant ,which showed statistical difference compared with before treatment (P<0 .05);the UA level after 1 week treatment in heart failure patients had statistical difference compared with before treatment (P<0 .05) .Conclu-sion The combined detection of BNP ,LDH ,UA and TnT has an important clinical significance in early diagnosis ,treatment and prognosis of cardiovascular diseases .