ABSTRACT
Objective To explore the clinic characteristics and pathological features of patients with colorectal cancer at different age .Methods A total of 144 cases diagnosed as colorectal cancer from Jan .2000 to Jun .2010 in this hospital were divided into two groups ,youth group (≤35 years old ,32 cases) and elderly group (≥60 years old ,112 cases) .The clinic characteristics and patho-logical features were analyzed retrospectively .Results Compared to elderly group ,the difference of bloody stools ,abdominal pain , abdominal discomfort ,mucinous adenocarcinoma ,Dukes staging and misdiagnosis rate in youth group was statistically significant (P<0 .05) .Conclusion Diagnostic accuracy of colorectal carcinoma in young patients is late ,misdiagnosis is high ,and colorectal carcinoma is more malignant ,and the prognosis is worse .
ABSTRACT
Objective:To study the expression and significance of P-gp and GST-?in colorectal carcinoma.Methods: Immunohistochemistry was used to examine the P-gp and GST-?expression in 78 cases of colorectal carcinoma and 31 cases of normal colorectal tissues.Resu/ts:The positive expression rates of P-gp and GST-?in colorectal carcinoma were 83.3% and 85.9% respectively,higher than those in normal colorectal tissues.The expression of P-gp was related to the degree of invasion(P