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Objective To explore the influence of Neuman theory on postoperative mental status of the patients with hypertensive cerebral hemorrhage. Methods According to their admission order, 120 patients with hypertensive intrac-erebral hemorrhage who accepted operation in our hospital from June 2011 to January 2014 were divided into the ex-perimental group and the control group, each group with 60 patients. The patients in the control group were treated with routine care while the patients in the experimental group were given psychological care interventions designed in ac-cordance with Neuman theory on the basis of the routine care. The nursing effects of the two groups were compared, detected and evaluated by Hamilton Depression Rationg Scale (HAMD) and Self-reporting inventory (SCL-90). Results The differences of HAMD total score of the two groups before interventions were not statistically significant. After 12 weeks intervention, HAMD total score of the experimental group significantly improved, especially in hopelessness, anxiety/somatization and cognitive impairment. The depression, anxiety, obsessive-compulsive symptoms, horror, hostility and psychosis of the experimental group were significantly lower than those of the control group after 12 weeks inter-vention. Conclusion Neuman theory has very high value of application to improve postoperative psychological status of the patients with hypertensive cerebral hemorrhage and is worthy of being promoted and applied in clinical work.
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Objective To explore the clinical manifestation,diagnosis and treatment of IgG4-related retroperitoneal fibrosis (IgG4-RRPF) and IgG4-related disease (IgG4-RD).Methods The clinical data of a case of IgG4-RRPF was analyzed retrospectively,the related literatures were reviewed,and a novel clinical entity IgG4-RD was introduced.Results The patient was a 52-year-old man with the complaint of left lower abdominal pain due to left hydronephrosis.CT and MRI revealed a soft tissue mass at the left psoas major muscle.PET-CT showed increased FDG uptake.After biopsy,the pathological diagnosis was consistent with IgG4-RD.The patient was diagnosed as IgG4-RRPF and treated with prednisone.The symptoms improved and retroperitonea] mass reduced.According to review the latest literatures,it is found that IgG4-RRPF was socalled idiopathic retroperitoneal fibrosis (IRF) formerly.Conclusion IgG4-RRPF is a rare disease in IgG4-RD spectrum,characterised by the presence of a retroperitoneal tissue,consisting of chronic inflammation and marked fibrosis,which often entraps the ureters or other abdominal organs.Hematological examination shows elevated serum IgG4 concentration (≥ 1.35 g/L).Histopathological examination shows marked tissue infiltration by lymphocytes and IgG4-plasma cells with fibrosis.Glucocorticoids are the first line of therapy.
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Purpose:To evaluate the effect of Auto-PBSCT combined with long-time low-dose interleukin-2 (after transplant) for increasing the rate of 5-year disease-free survival of lymphoid malignancies (ALL and NHL).Methods:U- sing chemotherapy combined with low dose G-CSF to mobilize peripheral blood stem cells,we carried out auto-PBSCT in lymphoid malignancies (7 cases CR_1 ALL、1 case CR_2 ALL、3 cases CR_1 NHL、5 cases refractory NHL).After transplant, 15 cases used low dose interleukin-2 at 5.10~5U/d for one year or longer.Results:7 cases CR_1 ALL are still alive,the aver- age disease-free survival is 73 months.Median disease-free survival is 51.5 months.2 of 3 cases CR_1 NHL are still alive. The 6 years disease-free survival in 10 cases CR_1 lymphoid malignancies(CR_1 NHL and CR_1 ALL) is 0.90?0.11,the aver- age disease-free survival is 66.8 months.In another PR (refractory) group of NHL and ALL (CR_2),3 years disease-free survival was 0.33?0.18,and average survival time was 20.66 months,but a chemotherapy-sensitive NHL is still alive (63 months),a case of lymphoblast cell NHL also survived for 46 months and died after relapse.Conclusions:Auto-PBSCT combined with long-turm low dose IL-2(after transplant) could effectively increase the rate of 5-year disease-free survival in CR_1 lymphoid malignancies(ALL and NHL).
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Purpose:To report three cases of myelodysplastic syndrome(MDS) transformed to atypical chronic myeloid leukemia(aCML).Methods:Compared the clinical findings,hemograms and bone marrow features in two different courses of the disease,discussed with review of related literatures.Results:The three patients were all old age.They onset with chronic anemia,the results of BM smear were MDS-RAS and MDS-RAEB;Then leukocytosis occurred in 6-65 months.The aCML were diagnosed according to the BM smear and normal chromosome.Conclusions:The MDS/MPD is a new category of the WHO classification that have both dysplastic and proliferative features.Atypical CML lacks the Ph chromosome and BCR/ABL fusion gene that are the hallmarks of classic CML.This kind of case is seldom seen.