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1.
Article in Chinese | WPRIM | ID: wpr-985451

ABSTRACT

In 2021, a total of 151 pregnant women were selected from the suburb of Shanghai. A questionnaire survey was conducted to obtain data about maternal age, gestational week, total annual household income, education level and passive smoking among pregnant women and one spot urine was collected. The concentrations of eight neonicotinoid pesticides and four metabolites in urine were measured by ultra-high performance liquid chromatography-tandem quadrupole time-of-flight mass spectrometry. The differences in detection frequencies and concentrations of neonicotinoid pesticides and their metabolites among pregnant women with different characteristics were compared, and the influencing factors of the detection of neonicotinoid pesticides in urine were analyzed. The results showed that at least one neonicotinoid pesticide was detected in 93.4% (141 samples) of urine samples. The detection frequencies of N-desmethyl-acetamiprid, clothianidin, thiamethoxam, and N-desmethyl-clothianidin were high, about 78.1% (118 samples), 75.5% (114 samples), 68.9% (104 samples), and 44.4% (67 samples), respectively. The median concentration of the sum of all neonicotinoid pesticides was 2.66 μg/g. N-desmethyl-acetamiprid had the highest detection concentration with a median concentration of 1.04 μg/g. A lower urinary detection frequency of imidacloprid and its metabolites was seen in pregnant women aged 30-44 years [OR (95%CI): 0.23 (0.07-0.77)]. A higher detection frequency of clothianidin and its metabolites was seen in pregnant women with per capita annual household income≥100 000 yuan [OR (95%CI): 6.15 (1.56-24.28)]. There was widespread exposure to neonicotinoid pesticides and their metabolites in pregnant women from the suburb of Shanghai, which might pose potential health risks to pregnant women, and maternal age and household income were potential influencing factors of the exposure to neonicotinoid pesticides.


Subject(s)
Humans , Female , Pregnancy , Pesticides/analysis , Pregnant Women , China , Neonicotinoids/analysis , Insecticides
2.
Chinese Journal of Epidemiology ; (12): 1092-1098, 2023.
Article in Chinese | WPRIM | ID: wpr-985638

ABSTRACT

Objective: To analyze the relationship between sedentary behavior and the force expiratory volume in 1 second (FEV1) reduction in middle-aged and elderly people in communities. Methods: The participants aged ≥40 years were randomly selected from a natural population cohort in Songjiang District, Shanghai, for pulmonary function tests and survey by using international physical activity questionnaire, a generalized additive model was used to analyze the association between sedentary behavior and FEV1 reduction in the study population and different sex-age subgroups. Results: A total of 3 121 study subjects aged ≥40 years were included. The prevalence of FEV1 reduction was 14.8%, which was higher in men than in women. There were 24.8% participants were completely sedentary. The prevalence of FEV1 reduction in women aged <60 years in complete sedentary group was 2.04 (95%CI: 1.11-3.72) times higher than that in non-complete sedentary group. In men aged <60 years, the prevalence of FEV1 reduction increased with daily sedentary time (OR=1.16, 95%CI: 1.04-1.29), and the prevalence of FEV1 reduction was also higher in those with sedentary time >5 hours/day than those with sedentary time ≤5 hours/day (OR=3.02, 95%CI: 1.28-7.16). The sensitivity analysis also found such associations. Conclusions: FEV1 reduction rate in age group <60 years was associated with sedentary behavior. Complete sedentary behavior or absence of moderate to vigorous physical activity played important roles in FEV1 reduction in women, while men were more likely to be affected by increased sedentary time, which had no association with physical activity. Reducing sedentary time to avoid complete sedentary behavior, along with increased physical activity, should be encouraged in middle-aged and elderly adults in communities to improve their pulmonary function.


Subject(s)
Male , Aged , Middle Aged , Humans , Adult , Female , Infant , Sedentary Behavior , China/epidemiology , Exercise , Surveys and Questionnaires , Prevalence
3.
Chinese Journal of Epidemiology ; (12): 260-268, 2022.
Article in Chinese | WPRIM | ID: wpr-935380

ABSTRACT

Objective: To analyze the diversity differences of gut microbiota between school-aged obese children and normal-weight children and identify the characteristic flora in obese children to provide some evidence for the subsequent study of the following study-related mechanisms and the prevention and treatment of obesity in school-aged children. Methods: This study was based on a cohort established in a primary school in Jiading district, Shanghai, 2016. Sixty-three children, including 43 boys and 20 girls, who were obese during the three years from 2016 to 2018, were enrolled in the obesity group. Among children who were average weight for three years, a total of 63 were selected as the control group, with matching with the obese ones in a 1 to 1 way according to age, sex and class. The primary characteristics, diet status, breastfeeding, and other information of children were collected by questionnaire. Fecal samples of participants in both groups were collected, and 16S rDNA sequencing was performed. Operable taxon units clustering according to 97% similarity and species annotation were based on the quality-optimized sequences. The difference in the diversity and genius of gut microbiota among children in the obesity and control groups were analyzed. The α diversity indices, including Ace, Chao1, Shannon, and Simpson index, were calculated. The β diversity was presented based on unweighted Unifrac distance and weighted Unifrac space by principal coordinate analysis. The differences in β diversity between the two groups were compared by similarity analysis (ANOSIM).The differences in genus distribution between the two groups were selected by STAMP software. The association of obesity with the α diversity and genus with significant differences were analyzed by the generalized linear model (GLM). Results: The Ace and Chao1 index in the obesity group was significantly lower than those in the control group (The P values were 0.026 and 0.039, respectively). There was no significant difference in Shannon and Simpson index between the two groups (The P values were 0.879 and 0.922, respectively). The results of ANOSIM showed differences in gut microbiota between the two groups (R>0), but the group contribution was not significant (unweighted Unifrac distance: R=0.006, P=0.223; weighted Unifrac distance: R=0.010, P=0.134). Among the obese group, the relative abundance of Prevotella and Sarcina was highest in the endemic genus. The STAMP results showed that the relative lots of 15 genera were significantly different between the two groups (P<0.05). The results of GLM showed that, compared with the control group, the obesity group had a lower level of the relative abundance in Akkermansia muciniphila, while a higher level in Coprococcus_3, Ruminococcus, Agathobacter and Collinsella. After stratification by sex, the Chao1 index was also lower in the obese boys than that in the normal-weight boys. However, the obese girls only had a higher level in Coprococcus_3 than the ordinary weight girls. Conclusions: Compared with children with average weight, obese children had lower α diversity of gut microbiota and lower relative abundance of dominant probiotics but had a higher relative lot of genus associated with metabolic disorders, inflammation promotion, and metabolism rate reduction.


Subject(s)
Child , Female , Humans , Male , China/epidemiology , Cohort Studies , Feces , Gastrointestinal Microbiome/genetics , Pediatric Obesity/epidemiology
4.
Chinese Journal of Epidemiology ; (12): 387-391, 2022.
Article in Chinese | WPRIM | ID: wpr-935400

ABSTRACT

Objective: To estimate the incidence of metabolic syndrome and explore possible risk factors for metabolic syndrome in adults of rural communities in Yuhuan county, Zhejiang province, China. Methods: During June-December, 2018, a follow-up survey was conducted in participants without metabolic syndrome at baseline survey in 2012 to obtain the information collected in questionnaire survey, anthropometric data and laboratory data. The incidence of metabolic syndrome in the participants was estimated, and Logistic regression model was used to explore the risk factors, adjusted risk ratio (aRR) and 95%CI. Results: Among 3 162 participants, 522 new metabolic syndrome cases were identified. The 6-year cumulative incidence rate of metabolic syndrome was 16.5%, and the cumulative incidence rate was higher in women (20.6%) than that in men (12.3%, P<0.001). Those incidence rates were higher in those in jobless, smoking or drinking groups. Being women (aRR=1.96, 95%CI: 1.50-2.58) and family history of hypertension (aRR=1.31, 95%CI: 1.04-1.63) were independent risk factors for metabolic syndrome. Conclusion: The follow up indicated that the incidence of metabolic syndrome was relatively high in rural adults on islands in Zhejiang, and women or those with family history of hypertension were more likely to have metabolic syndrome.


Subject(s)
Adult , Female , Humans , Male , Incidence , Islands , Metabolic Syndrome/epidemiology , Risk Factors , Rural Population
5.
Article in Chinese | WPRIM | ID: wpr-940940

ABSTRACT

On February 2022, WHO released the evidence-based guideline on control and elimination of human schistosomiasis, with aims to guide the elimination of schistosomiasis as a public health problem in disease-endemic countries by 2030 and promote the interruption of schistosomiasis transmission across the world. Based on the One Health concept, six evidence-based recommendations were proposed in this guideline. This article aims to analyze the feasibility of key aspects of this guideline in Chinese national schistosomiasis control program and illustrate the significance to guide the future actions for Chinese national schistosomiasis control program. Currently, the One Health concept has been embodied in the Chinese national schistosomiasis control program. Based on this new WHO guideline, the following recommendations are proposed for the national schistosomiasis control program of China: (1) improving the systematic framework building, facilitating the agreement of the cross-sectoral consensus, and building a high-level leadership group; (2) optimizing the current human and livestock treatments in the national schistosomiasis control program of China; (3) developing highly sensitive and specific diagnostics and the framework for verifying elimination of schistosomiasis; (4) accelerating the progress towards elimination of schistosomiasis and other parasitic diseases through integrating the national control programs for other parasitic diseases.


Subject(s)
Humans , China/epidemiology , Disease Eradication , Public Health , Schistosomiasis/prevention & control , World Health Organization
6.
Article in Chinese | WPRIM | ID: wpr-940942

ABSTRACT

Schistosomiasis is a parasitic disease that seriously hinders socioeconomic developments and threatens public health security. To achieve the global elimination of schistosomiasis as a public health problem by 2030, WHO released the guideline on control and elimination of human schistosomiasis on February, 2022, with aims to provide evidence-based recommendations for schistosomiasis morbidity control, elimination of schistosomiasis as a public health problem, and ultimate interruption of schistosomiasis transmission in disease-endemic countries. Following concerted efforts for decades, great achievements have been obtained for schistosomiasis control in China where the disease was historically highly prevalent, and the country is moving towards schistosomiasis elimination. This article reviews the successful experiences from the national schistosmiasis control program in China, and summarizes their contributions to the formulation and implementation of the WHO guideline on control and elimination of human schistosomiasis. With the progress of the "Belt and Road" initiative, the world is looking forward to more China's solutions on schistosomiasis control.


Subject(s)
Humans , China/epidemiology , Disease Eradication , Public Health , Schistosomiasis/prevention & control , World Health Organization
7.
Article in Chinese | WPRIM | ID: wpr-904621

ABSTRACT

Objective To evaluate the impact of water pollutants, water levels and meteorological factors on the Oncomelania hupensis density in Eastern Dongting Lake regions, so as to provide insights into schistosomiasis control. Methods O. hupensis snails were surveyed using a systematic sampling method in snail-infested marshlands in Eastern Dongting Lake regions from 2007 to 2014, and data pertaining to water pollutants, water levels and meteorological factors were collected. The duration of submergence and the date of the start of submergence were calculated. The snail density and its influencing factors were descriptively analyzed, and a linear mixed model was generated to examine the impacts of variables on the snail density. In addition, smooth curves were fitted to investigate the relationship between snail density and variables. Results The snail density appeared a fluctuation in Eastern Dongting Lake regions during the period from 2007 to 2014, with the highest density on October, 2010 (52.79 snails/0.1 m2) and the lowest density on January 2009 (2.15 snails/0.1 m2). Linear mixed-model analysis showed that permanganate index, total phosphorus and the date of the start of submergence affected the snail density (t = 6.386, −2.920 and −3.892, all P values < 0.01). Smooth curve analysis revealed that the associations of the snail density with the permanganate index and total phosphorus appeared an approximately quadratic curve. After the end of April, the earlier date of the start of submergence resulted in a higher snail density. Conclusion Permenganate index, total phosphorus and the date of the start of submergence affect the O. hupensis snail density in Eastern Dongting Lake regions.

8.
Article in Chinese | WPRIM | ID: wpr-907101

ABSTRACT

This study introduces the current status of the coronavirus disease 2019 (COVID-19) epidemic, the adjustment of response initiatives, and the global variation of novel coronaviruses and vaccination in Europe, the United States, Japan, and Singapore. It summarizes the achievements in prevention and control efforts in China during COVID-19 epidemic. In addition, it describes the key public health issues in Chinese response strategy that includes: promoting the establishment of a population immunization system; optimizing health certification by unifying health codes, trip codes, and vaccine passes as a triple-identification at the national level; retaining nucleic acid testing as a technical means of detecting the source of infection and epidemiological investigation of close contacts; adhering to the requirements of public places, public transportation and other measures such as wearing masks; strengthening the surveillance of COVID-19 and respiratory infectious diseases; normalizing the timing of implementation of prevention and control strategies.

9.
Article in Chinese | WPRIM | ID: wpr-907124

ABSTRACT

This study introduces the current status of the coronavirus disease 2019 (COVID-19) epidemic, the adjustment of response initiatives, and the global variation of novel coronaviruses and vaccination in Europe, the United States, Japan, and Singapore. It summarizes the achievements in prevention and control efforts in China during COVID-19 epidemic. In addition, it describes the key public health issues in Chinese response strategy that includes: promoting the establishment of a population immunization system; optimizing health certification by unifying health codes, trip codes, and vaccine passes as a triple-identification at the national level; retaining nucleic acid testing as a technical means of detecting the source of infection and epidemiological investigation of close contacts; adhering to the requirements of public places, public transportation and other measures such as wearing masks; strengthening the surveillance of COVID-19 and respiratory infectious diseases; normalizing the timing of implementation of prevention and control strategies.

10.
Article in Chinese | WPRIM | ID: wpr-881474

ABSTRACT

Since July 2020, nucleic acids of novel coronavirus SARS-CoV-2 were frequently detected in cold chain food imported to China, making imported food being a potential risk to the COVID-19 outbreak. Based on the epidemiological characteristics of SARS-CoV-2, imported cold-chain food and their packaging may become the carriers of SARS-CoV-2 in long-distance cross-border transportation. In each aspect of stakeholders including governmental supervision, manufacturers and consumers, China should strengthen the risk management of imported cold-chain food to ensure the safety, especially pay attention to the health protection of industry workers in close contact with cold -chain food.

11.
Article in Chinese | WPRIM | ID: wpr-881501

ABSTRACT

The earthquake occurred in Japan on March 11, 2011 was accompanied by a tsunami, which also led to a leakage accident at the Fukushima Daiichi nuclear power plant. The disaster caused large-scale casualties and property damage. Soma City in Fukushima Prefecture established a disaster response headquarter and held its first meeting 9 minutes after the earthquake. Disaster response can be divided into three stages. In the first phase, life protection is the primary task. In the second phase, the primary tasks are health protection and basic life support. And in the third phase, life quality improvement is the primary task. This article reviewed the public health emergency response of local governments in Japan after the disaster in order to improve the response to public health emergencies in China.

12.
Article in Chinese | WPRIM | ID: wpr-881502

ABSTRACT

Neonicotinoid is a kind of neuroactive pesticide, and it has become the most widely used pesticide in the world. In recent years, neonicotinoid has been detected in the environment and food, suggesting that human can be exposed to this kind of pesticide through drinking water, ingestion and respiration, which poses potential health hazards to human. However, there is no comprehensive report on the pollution level of neonicotinoid pesticides in the environment and food and the impact on human health. In this paper, the pollution status, population exposure level and potential health risks of neonicotinoid pesticides in water, air and food were reviewed. We found that neonicotinoid residues are widespread in fruits and vegetables, of which imidacloprid has the highest detection rate. Except for a few samples with excessive neonicotinoid detection, the detection level in most samples did not exceed national food safety standards. A variety of neonicotinoid pesticides have been detected in the air, surface water, tap water and drinking water. External exposure studies in the population have shown that ingestion is the main route of exposure to neonicotinoid, and the external exposure level is much lower than its chronic reference dose. The internal exposure study mainly detected the concentration of neonicotinoid pesticides and their metabolites in urine. A variety of neonicotinoid pesticides and their metabolites are detected in urine, and the concentration range is ng/ml level. Internal exposure studies found that the detection rate of thiamethoxam and dinotefuran in urine is higher, and the detection rate of neonicotinoid in Asian countries is higher than that in European and American countries. Occupational exposure studies found that neonicotinoid exposure levels increased after pesticide spraying, and the exposure levels in rural areas where pesticides were commonly used were higher than those in neighboring urban areas. Animal experiments have found that neonicotinoid pesticides have reproductive toxicity, genetic toxicity, neurotoxicity, immunotoxicity, liver toxicity and nephrotoxicity to non-target organisms. Cell experiments suggest that neonicotinoid is an endocrine disruptor. The symptoms of acute exposure in humans are related to the exposure dose, route and physical condition of the exposed person, which ranges from mild symptoms (nausea, vomiting, headache and diarrhea) to death. Population epidemiological studies have shown that chronic exposure to neonicotinoid pesticides is associated with adverse health effects in humans such as neonatal tetralogy of Fallot, anencephaly, and adverse mental symptoms.

13.
Article in Chinese | WPRIM | ID: wpr-882210

ABSTRACT

Objective:To investigate the association of alcohol drinking and the incident risk of type 2 diabetes in men and to provide evidences for early prevention of diabetes. Methods:Rural adult males without diabetes in Deqing County, Zhejiang Province were enrolled. A dynamic prospective cohort study was conducted. Data were collected through questionnaires, physical examination, experimental measurements and a electronic follow-up database. Cox multivariate regression was performed to assess the association of alcohol drinking and the incident risk of type 2 diabetes in men. Results:During the follow-up period (7.15±2.90 years), 354 men developed diabetes, and the incidence rate was 4.15/1 000 person-years. After adjusting for confounding factors, the incident risk of type 2 diabetes among the men with high alcohol drinking frequency (≥7 times/week) and low single alcohol intake (0.1-19.9 g/occasion) was lower than that among non-alcohol drinkers, and the value of HR (95%CI) was 0.72 (0.56-0.94) and 0.54 (0.30-0.99), respectively. Consumption of ≥40.0 g alcohol per occasion 3-6 times a week increased the incidence of type 2 diabetes, and consumption of <40.0 g alcohol per occasion over 7 times a week decreased the incidence of type 2 diabetes, with the value of HR (95%CI) of 1.53 (1.02-2.30) and 0.52 (0.28-0.99) respectively. Conclusion:Different alcohol drinking patterns affect the incident risk of type 2 diabetes among rural adult males in Deqing County. Further study on alcohol drinking and diabetes may have ethical and practical significance for the prevention and control of diabetes in rural China.

14.
Article in Chinese | WPRIM | ID: wpr-876161

ABSTRACT

Objective:To model an outbreak of coronavirus disease 2019 (COVID-19) in Shijiazhuang and forecast its spread trend. Method:We collected confirmed COVID-19 cases from the Health Commission of Hebei Province during the period of January 2 to January 27, 2021. We built a new model (SEIaIcRK), including the contribution of asymptomatic cases, based on the traditional SEIR model to explore and analyze the transmission of COVID-19. Results:A total of 863 confirmed cases were reported during the study period (ended on January 27, 2021). Our model fitted well with the daily cumulative incidence data and showed that the effective reproductive number decreased sharply from 3.80 on January 2 to 1.54 on January 4, then further decreased to <1 afterwards. Our model also predicted that number of COVID-19 cases would not increase after Feb 16, 2021. Conclusion:The SEIaIcRK model can be used to predict the spread trend of COVID-19 in Shijiazhuang. The current COVID-19 countermeasures effectively contain the disease spread.

15.
Article in Chinese | WPRIM | ID: wpr-876170

ABSTRACT

Objective:To characterize the mortality rate of residents in Minhang District of Shanghai from January to April in 2016-2020, and to determine the change in the epidemic Coronavirus Disease 2019 (COVID-19) in 2020. Methods:Data of mortality surveillance was collected from the death registry of Shanghai residents. Cause of death was coded and classified per the International Classification of Diseases (ICD-10). The standardized mortality rate was calculated based on the standard population of China in 1990. The analysis was performed by Excel 2016 and SPSS 20.0. Results:From 2016 to 2020, the average crude mortality rate of residents was 281.75/100 000 from January to April in Minhang District of Shanghai, and the standardized mortality rate was 66.57/100 000. The top five causes of death in the latest five years were cardiovascular diseases, tumor, respiratory diseases, endocrine diseases, and injury and poisoning. The mortality rate was the lowest from January to April in 2020 in the past five years; furthermore, the mortality rate of respiratory system diseases has decreased significantly. Conclusion:Sex, age, place and causes of death in residents are consistent from January to April across years in Minhang District of Shanghai. However, there are minor differences in 2020, which may be attributable to the epidemic of COVID-19.

16.
Article in Chinese | WPRIM | ID: wpr-792883

ABSTRACT

Novel coronavirus pneumonia disease (COVID-19) caused by SARS-CoV-2 began to emerge in Wuhan, Hubei, China in December 2019. It is currently spreading globally including Japan. The COVID-19 case in Japan began to appear in middle January 2020 and continued to increase over time. The period from middle January to the end of February is considered to be the initial stage of domestic transmission in Japan. This article described the spread of 935 COVID-19 cases related to Japan by the end of February 2020, including the 15 infected Japanese returned from Wuhan, the 696 infected individuals in the large-scale cruise ship 'Diamond Princess' and the 224 infected individuals in Japan. This paper summarizes the measures to control the spread of SARS-CoV-2 in Japan, such as limiting RT-PCR detection for SARS-CoV-2, reducing the number of patients with mild illness who go to medical institutions unnecessarily, formulating guidelines for SARS-CoV-2 infection consultation, canceling large gatherings and temporarily closing schools. This paper further points out the problems encountered in the prevention and control of the spread of SARS-CoV-2 in Japan, such as the slow detection of RT-PCR, the risk of infection faced by medical staff, the regional differences in the domestic health care service system, the confusion of information disclosure and management. The above introduction as allows us to acquire a better understanding of the new coronavirus pneumonia in Japan and the world and may provide reference for the control the epidemic of COVID-19 in worldwide.

17.
Article in Chinese | WPRIM | ID: wpr-821623

ABSTRACT

Objective To evaluate the effects of water body environments on the microbial community of Oncomelania hupensis snails in marshlands of the eastern Dongting Lake where natural extinction of O. hupensis snails are found, so as to explore the correlation between the natural extinction of O. hupensis snails and the microbial community in snails. Methods Snails were caged water bodies in the Qianliang Lake marshland (Qianliang Lake regions) where natural extinction of snails was found and in the Junshan Park marshland (Junshan Park regions) in the eastern Dongting Lake for 30 days, and then all snails were collected and identified for survival or death. DNA sequencing of the fungi and bacteria was performed in snails before and after immersion in waters, and the biodiversity and abundance were analyzed. Results The survival rates of O. hupensis snails were 28.0% (70/250) and 64.8% (162/250) in Qianliang Lake regions and Junshan Park regions 30 days after immersion in waters, respectively (χ2 = 81.365, P < 0.01). The number of the fungal community and the biodiversity of the bacterial community were both greater in snails caged in Qianliang Lake regions post-immersion than pre-immersion, and there was a significant difference in the structure of the fungal and bacterial communities. The microbial community with a significant difference included Flavobacteriaceae,which was harmful to O. hupensis snails. Conclusion The water body environment affects the composition of the microbial community in O. hupensis snails in marshlands with natural snail distinction around the eastern Dongting Lake; however, further studies are required to investigate whether the natural distinction of snails is caused by water body environments-induced changes of the microbial spectrum in O. hupensis snails.

18.
Article in Chinese | WPRIM | ID: wpr-821661

ABSTRACT

As an ancient parasitic disease, schistosomiasis has been endemic in Dongting Lake areas for more than 2 100 years. In the early 20th century, the first human case of schistosomiasis in China was reported in Dongting Lake areas, which was paid extensive attention. After the founding of the People’s Republic of China, large-scale schistosomiasis control activities were launched promptly in Dongting Lake areas, and great successes have been achieved following the three stages of control efforts, including the snail control-based stage, synchronous chemotherapy for humans and livestock-based control stage and infectious source control-based control stage. In 2015, transmission control of schistosomiasis was achieved in Hunan Province. This paper comprehensively describes the discovery and control of schistosomiasis, analyzes the challenges for the current schistosomiasis control programs and proposes the emphasis for future control activities in Dongting Lake areas, so as to provide insights into the schistosomiasis control program in this area.

19.
Article in Chinese | WPRIM | ID: wpr-876322

ABSTRACT

Beta coronaviruses (β-CoVs) can infect human and a variety of animals, causing respiratory, intestinal, liver and nervous system diseases of the hosts.Since the outbreak of severe acute respiratory syndrome (SARS) caused by coronavirus in 32 countries and regions in 2002, there have been Middle East respiratory syndrome and human coronavirus HKU1 pneumonia caused by other viruses of this genus.β-CoVs pose a continuous threat to human health with its high transmission efficiency, serious infection consequences and uncertain epidemic outbreaks.Hereby, the epidemic history, virus sources and transmission modes of β-CoVs, as well as the detection and monitoring methods for the virus are reviewed in the paper to provide ideas and measures for better control of human diseases caused by β-CoVs.

20.
Article in Chinese | WPRIM | ID: wpr-876339

ABSTRACT

Beta coronaviruses (β-CoVs) can infect human and a variety of animals, causing respiratory, intestinal, liver and nervous system diseases of the hosts.Since the outbreak of severe acute respiratory syndrome (SARS) caused by coronavirus in 32 countries and regions in 2002, there have been Middle East respiratory syndrome and human coronavirus HKU1 pneumonia caused by other viruses of this genus.β-CoVs pose a continuous threat to human health with its high transmission efficiency, serious infection consequences and uncertain epidemic outbreaks.Hereby, the epidemic history, virus sources and transmission modes of β-CoVs, as well as the detection and monitoring methods for the virus are reviewed in the paper to provide ideas and measures for better control of human diseases caused by β-CoVs.

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