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Objective @#To estimate the prevalence and risk factors of suicide ideation,suicide planning and suicide attempts among middle school students and to provide reference for suicide intervention.@*Methods @#The students of grade 7 to 12 in Ningbo were recruited through multi-stage random sampling method. A self-reported questionnaire survey was conducted to collect the information about suicide ideation,suicide planning and suicide attempts within 12 months. A multivariate logistic regression model was used to analyze the risk factors for the three aspects of suicide among middle school students.@*Results@# A total of 10 729 questionnaires were sent out and 10 726 valid ones were collected,with a validity rate of 99.97%. The prevalence rates of suicide ideation,suicide planning and suicide attempts among middle school students during the last 12 months were 12.93%,4.54% and 5.06%,respectively. The results of multivariate logistic regression analysis indicated that females（OR：1.397-1.575,95%CI：1.178-1.927）,students of grade 7 to 9（OR：1.625-1.824,95%CI：1.323-2.082）,poor health condition（OR：1.160-2.131,95%CI：1.005-2.985）,loneliness（OR：1.574-4.423,95%CI：1.221-5.254 ）,desperation（OR：2.796-3.232,95%CI：2.400-3.990）,anxiety（OR：1.890-2.117,95%CI：1.503-2.496）,less than 8 hours a day of sleep（OR：1.152-1.263,95%CI：1.030-1.594）,smoking（OR：1.476-2.074,95%CI：1.055-3.072）,drinking（OR：1.479-1.863,95%CI：1.271-2.296）,fighting（OR：1.716-1.941,95%CI：1.330-2.422）and school bullying（OR：2.254-3.292,95%CI：1.342-5.277）were common risk factors for suicide ideation,suicide planning and suicide attempts;physical activity（OR：0.597-0.720,95%CI：0.474-0.923）was a common protective factor for suicide ideation,suicide planning and suicide attempts.@*Conclusion @#Females,lower grade,poor health condition,loneliness,desperation,anxiety,lack of sleep,smoking,drinking,fighting,school bullying and physical activity were influencing factors for suicidal behaviors.
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Objective To determine the efficacy of lifestyle interventions in adults with impaired glucose tolerance (IGT).Methods MEDLINE (Pub Med),EMBASE,Science Citation Index (SCI),and Cochrane Database were retrieved for articles about the relations of lifestyle intervention and IGT.Searches were limited to English language publications.The RCTs outcome evaluated in this study included 2 h plasma glucose level and fasting plasma glucose,meta-analysis was carried oat by Stata 11.0 among articles for the inclusion and exclusion criteria.The difference of effects was expressed as standardized mean deviation(SMD).Results A total of 10 RCTs studies met the inclusion criteria.Lifestyle interventions were associated with a decline in 2 h plasma glucose and fasting plasma glucose level (SMD =-0.67,P＜0.01 ;SMD =-0.33,P＜0.01),but high heterogeneity was identified in this meta-analysis.Conclusion Physical,dietary and both combined interventions can reduce 2-h plasma glucose and fasting plasma glucose levels in adults with impaired glucose tolerance.As high heterogeneity was identified in this meta-analysis,more high quality research is needed.
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Objective To investigate the mixed model in bier-archical classification datas and implementing with mixed model in SAS. Methods Hierarchical classification datas exemplify the mixed model u-sing procedure mixed,and compared with traditional general linear model. Results The example shows the same result between the SAS mixed model and the general linear model. Conclusion SAS MIXED can flexi-bly fit and analysis hieraxchical classification datas.
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0.05) at 8 w. At 8 w body fat and TG in groups B and C were significantly lower than group A (P
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Objective To investigate the effects of myricetin (Myr) on A549 lung cancer cell proliferation and its mechanism. Method The inhibitory effects of Myr on the growth of A549 cells were investigated and its value of IC50 after 72 h incubation was measured by 3-(4,5-dimethyl-thiazolyl -2)-2,5-diphenyl tetrazolium bromide (MTT) method. The phosphorylation level of Akt protein was studied by Western blotting. Results Myr inbibited A549 cell proliferation in dose-dependent way. The IC50 value of Myr treatment for 72 h was 41.7 ?g/ml. Treatments with 32 ?g/ml Myr for 12 h significantly reduced the protein kinase B (Akt Ser473) phosphorylation. Conclusion Myr could inhibit the growth of A549 cell in a dose-dependent way. Akt phosphorylation may be the mainly molecular target of Myr in A549.