ABSTRACT
17 patients with maxillary antral pseudocyst underwent side wall fenestration with simultaneous implantation of 38 implants and the upper denture repair, follow-up observation was conducted after repair for 6 to 24 months (an average of 11. 4 months) . Good osseointegration was observed in all cases. No implant shedding or bone resorption occurred during the follow-up period, and the antrol pseudo cyst disappeared or decreased. Dental implantation simulataneously with maxillary sinus augmentation is effective in the management of maxillary implantation for the cases with antrol pseudocyst.
ABSTRACT
<p><b>BACKGROUND AND OBJECTIVE</b>Precious studies proven that aberrant tyrosine phosphorylation has linked with cancer. The aim of this work is to study the expression and significance of SHP2 in non-small cell lung cancer (NSCLC) through tissue microarray technique and immunohistochemical method.</p><p><b>METHODS</b>Eighty NSCLC specimens were constructed into tissue microarray and performed using immunohistochemistry.</p><p><b>RESULTS</b>The total positive rates of SHP2 were 70.7% (56/80) in NSCLC, 72.5% (29/40) in squamous cell carcinoma and 75% (27/40) in adenocarcinoma, which was not significant difference in sex, age, the size of tumor, histology, clinical stages and differentiation (P > 0.05), the positive rates of SHP2 were significantly higher in the cases with lymphnode metastasis than those without (P < 0.05).</p><p><b>CONCLUSION</b>The expression rate of SHP2 is high and closely correlated to lymphnode metastasis in NSCLC, which implies the occurrence and development of lung cancer maybe related to SHP2, and SHP2 maybe a new marker and therapeutic targets for lung cancer.</p>
Subject(s)
Female , Humans , Male , Middle Aged , Adenocarcinoma , Metabolism , Pathology , Carcinoma, Non-Small-Cell Lung , Metabolism , Pathology , Carcinoma, Squamous Cell , Metabolism , Pathology , Immunohistochemistry , Lung Neoplasms , Metabolism , Pathology , Lymphatic Metastasis , Pathology , Protein Tyrosine Phosphatase, Non-Receptor Type 11 , Metabolism , Tissue Array AnalysisABSTRACT
Objective To observe the multi-slice spiral CT manifestations of cavernous transformation of the portal vein (CTPV) secondary to tumor emboli from hepatocellular carcinoma (HCC). Methods MSCT manifestations of 31 patients of HCC with tumor emboli-induced CTPV proved by operation and pathology were collected and the data were retrospectively analyzed. Results Tumor embolus was detected in both the trunk, left and right branches of PV in 23 patients, accompanied with superior mesenteric vein and/or splenic vein and inferior vena cava's tumor embolus in 4 and infiltration of gallbladder in 1 of 23 patients, as well as in the trunk and left branch in 1, and in the trunk and right branch of PV in 5 patients, accompanied with right hepatic vein and/or inferior vena cava's tumor embolus in 2 and in the portal trunk and superior mesenteric vein in 1, only in the right branch in 1 patient, respectively. Tumor emboli were isodense in plain CT scan, but enhanced with obvious degrees in arterial phase and filling defects in portal venous phase. There were collateral vessels around portal vein. Lateral branches around hilar bile duct, the open of venous plexus around fossa of gallbladder, lateral veins around gastric fundus and lesser curvature, lateral veins of lower part of esophagus and expansion of splenic vein were found in 31 (100%), 19 (61.29%), 21 (67.74%), 7 (22.58%) and 15 patients (48.38%), respectively. Conclusion Tumor emboli-induced CTPV from HCC has specific MSCT findings being helpful to the diagnosis.