ABSTRACT
Objective To analyze of the efficacy of minimally invasive surgery combined with medication in the treatment of ureteral calculi.Methods From June 2013 to June 2015,124 patients with ureteral calculi which confirmed by X-ray in our hospital were collected as subjects.According to the treatment method,they were divided into control group and observation group,patients in the control group were treated with simple medication,while the observation group were treated with minimally invasive surgery combined with drug therapy.The effects of treatment and the levels of MCP-1,TFF1 and HMGB1 in urine between two groups were compared.Results The stone expulsion rate and the net rate of the observation group was higher than those of the control group,the differences were significant(P<0.05).The stone expulsion time of observation group was shorter than that of the control group,the formation rate of the observation group was lower than that of the control group,the differences were significant(P<0.05).Adverse reactions occurred in 11 cases of the observation group,in 29 cases of the control group,the incidence of adverse reactions in the observation group was lower than that in the control group,the difference was significant(P<0.05).After the treatment,17 cases of adverse drug reactions occurred in the observation group,which was more than 5 cases of adverse drug reactions in the control group,the difference was significant(P<0.05).After treatment,the levels of MCP-1 and HMGB1 in urine of two groups were decreased compared with those before treatment,the level of TFF1 was increased,the differences were significant(P<0.05);while the levels of MCP-1 and HMGB1 of the observation group after treatment were lower than those of the control group,the level of TFF1 was higher than that of the control group,the difference was significant(P<0.05).The effective rate of the observation group was 88.71％,which higher than 69.35％ of the control group,the difference was significant(P<0.05).Conclusion On the basis of medication,combined with extracorporeal shock wave lithotripsy for ureteral calculi can not only improve the therapeutic effect,but also reduce the risk of adverse reactions.
ABSTRACT
Objective] To evaluate the therapeutic effect of treatment with tonifying qi and activating blood Chinese medicine combined with cultivate intervention therapy for angina. [Methods]210 patients with angina were divided into three groups: the control group 1 (60), control group 2 (60) and observation group(90), in accordance with the principle of randomization. There were 90 patients in each group. In the acute stage, the control group and observation group were given nitroglycerin administering. In remission stage, the control group were treated with conventional western medicine treatment, the observation group was added with the therapy tonifying qi and activating blood Chinese medicine. The course was six weeks. The extent and attacking times and the duration of the disease were compared after the treatment. [Results] (1)After treatment, the attack times and duration times of the symptom were reduced in two groups(P0.05). (2) After treatment, in the control group1, the total effective rate was 75.00%, in the control group 2, the total effective rate was 85.00%,while in the observation group, the total effective rate was 91.11%. There had an obvious difference among three groups(P<0.05 or P<0.01). [Conclusion] The treatment with tonifying qi and activating blood Chinese medicine combined with intervention therapy can reduce patients' attack times, relieve their symptoms on improving the effect of angina, worth large-sample study in clinic.