ABSTRACT
Objective To investigate the effects of long-term,low-dose hormone replacement therapy(HRT) on serum level of creactive protein(CRP) and homocysteine(Hcy) in postmenopausal women.Methods A total of 141 postmenopausal women were selected from medical staff of the Peking Union Medical College Hospital.Of these,63 subjects have been treated with low-dose sex hormone for over 5 years(HRT group),78 subjects have never received hormone replacement therapy as control group.The serum levels of CRP and Hcy in two groups were evaluated.Results The serum level of estradiol(E_2) in HRT group was significant higher than that in control group(median,inter-quartile range;33.8 ng/L,30.9 vs 21.3 ng/L,33.2)(P0.05).There was no correlation between the serum level of CRP,Hcy and the plasma levels of E_2 and FSH respectively.Conclusion Long-term and low-dose HRT does not increase the serum level of CRP and Hcy in postmenopausal women.
ABSTRACT
RIA of LH and FSH in 437 cases and PRLin 287 cases of secondary amenorrhea were performed. According to the results they can be divided into 5 groups: hypergonadotropic amenorrhea 132 cases (30.2%), hypogonadotropic amenorrhea 44 cases (10.1%), normogonadotropic amenorrhea 40 cases (9.1%), amenorrhra with increased LH/FSH ratio 94 cases (21.5%) and hyperprolactinemic amenorrhea 127 cases of which 117 cases (92.1%) had galactorrhea. The clinical features, laparoscopy findings and results of treatment were presented.