ABSTRACT
Objective@#To investigate the clinical efficacy of reduced port laparoscopic radical resection on colorectal cancer.@*Methods@#Clinical data of 46 patients with colorectal cancer undergoing reduced port laparoscopic radical resection were retrospectively analyzed.@*Results@#All of 46 patients underwent laparoscopic surgery, with an average operation time of 206 minutes, an average intraoperative bleeding of 56 ml, an average number of lymph nodes removement of 12/case (ranged from 6 to 21). One case had incision infection, 2 cases had anastomotic leakage, and they all recovered and discharged after treatment.@*Conclusions@#Reduced port laparoscopic radical resection of colorectal cancer is safe and feasible, reduces labor costs, and has a good clinical efficacy, which is worthy of clinical promotion.
ABSTRACT
Objective To investigate the clinical efficacy of reduced port laparoscopic radical resection on colorectal cancer.Methods Clinical data of 46 patients with colorectal cancer undergoing reduced port laparoscopic radical resection were retrospectively analyzed.Results All of 46 patients underwent laparoscopic surgery,with an average operation time of 206 minutes,an average intraoperative bleeding of 56 ml,an average number of lymph nodes removement of 12/case (ranged from 6 to 21).One case had incision infection,2 cases had anastomotic leakage,and they all recovered and discharged after treatment.Conclusions Reduced port laparoscopic radical resection of colorectal cancer is safe and feasible,reduces labor costs,and has a good clinical efficacy,which is worthy of clinical promotion.
ABSTRACT
Objective To extract the sulfated polysaccharides from Grateloupia turuturu Yamada and to studyits physico-chemical properties and antiviral activities.Methods The sulfated polysaccharides were extracted from Grateloupia turuturu Yamada by hot water extraction and alcohol precipitation.Two pure polysaccharides were obtained by DEAE-52 cellulose column chromatography.The physico-chemical properties including the composition of the glycoconjugate and the content of the sulfate were analyzed.The antiviral effects of the samples on HSV-1,Cox_(3) and their cytotoxicity to Vero,Hela cell were studied by cytopathic effect(CPE) reduction assay and MTT colorimetric assay.Results The results showed that the glycoconjugate was composed of Gal and slight Glc,Xyl etc.The content of the sulfate group was more than 15%.And the polysaccharides showed good antiviral activities,especially the pure polysaccharides.Their 50% inhibited concentrations(IC_(50))on HSV-1 were(7.81) and 3.91?g?mL~(-1),selectivity index(SI)values were larger than 128 and 256,respectively.Conclusion The sulfated polysaccharides from Grateloupia turuturu Yamada have good antiviral effects on HSV-1 and Cox_(3).