ABSTRACT
To explore the changes of anti-thyroid drug (ATD) on bone mineral density and bone turnover parameters in patients with Graves disease (GD).Compared with the healthy controls during the same period,the serum levels of alkaline phosphatase (AKP) and bone gla protein (BGP) in GD patients significantly increased at pre-treatment and after normal thyroid by treatment (P ＜ 0.05,P ＜ 0.01).AKP and BGP of GD patients reduced to normal level at Month 6 after normal thyroid (P ＞ 0.05) ; BMD significantly decreased at pre-treatment and Month 12 after normal thyroid (P ＜ 0.05,P ＜ 0.01).And it dropped to normal level at Month 18 (P ＞ 0.05).GD could affect bone metabolism and thyroid hormone might accelerate bone metabolism directly.
ABSTRACT
A total of 74 patients undergoing arthroscopic reconstruction for anterior cruciate ligament (ACL) injury from January 2007 to September 2009 were randomly divided into the treatment and control groups.The treated patients started training at day 1 post-operation while the controls had initial external plaster fixation for 4 - 6 weeks followed by supporting devices with active and passive functional exercises of knee flexion and extension.All Lysholm scores in two groups were better at Month 12 than those at Month 3 [(93.8±2.7)vs.(81.8±4.2),(80.0±7.6) vs.(75.2±4.2); t=2.85,P＜0.0l,t=2.16,P＜0.05,respectively].The scores in the treatment group achieved better curative effects than those in the control group at Months 3,6 and 12 (P ＜0.01 ) ; Early and standard rehabilitation training for the patients with ACL injury of knee after reconstruction will facilitate the recovery of knee joint fumction.