Effectiveness of pretreatment prednisolone on postendodontic pain in comparison to placebo

The objective of the study was to compare the effectiveness of pretreatment prednisolone on post-endodontic pain in comparison with placebo. Patients of irreversible pulpitis were arbitrarily divided into two equal groups [group A and group B] each comprising of 45 patients. In group A premedication [prednisolone] was given and in group B placebo was given. Pain level was evaluated on visual analogue scale as no, mild, moderate or severe pain according to score. The overall effectiveness was noted after 24 hours. It was concluded that Pretreatment prednisolone was more effective for prevention of Postendodontic [PEP] pain in comparison to placebo