ABSTRACT
OBJETIVOS: Determinar o aporte nutricional de iodo na população estudada e correlacionar os níveis de iodo encontrados em amostras casuais de urina (iodúria) com alterações anatomopatológicas observadas nas tireoides dessa população. MATERIAIS E MÉTODOS: Determinou-se a iodúria em 30 amostras casuais de urina e realizou-se o estudo anatomopatológico de 55 tireoides colhidas de cadáveres que deram entrada no Departamento Médico Legal de Vitória, Espírito Santo, Brasil, no período de maio a agosto de 2011. RESULTADOS: Em 29 amostras de urina (96,7%) encontrou-se iodúria acima do limite máximo preconizado pela Organização Mundial da Saúde (OMS) de 300 µg/L. Em 14 tireoides (25,5%) foi identificada a presença de quadros histológicos compatíveis com tireoidite. Níveis mais elevados de iodo na urina foram observados no sexo feminino e nos casos de tireoides com presença de achados inflamatórios (tireoidites). CONCLUSÕES: Podemos concluir que na população estudada houve um excesso de iodo em seu aporte nutricional e uma maior incidência de quadros inflamatórios tireoidianos.
OBJECTIVES: To determine iodine nutrition in the population and to correlate levels of iodine found in random samples of urine with pathological changes observed in thyroids collected in this population. MATERIALS AND METHODS: Urinary iodine was determined in 30 random samples of urine and the pathological study was carried out in 55 thyroid glands from corpses received by the Department of Forensic Medicine of Vitória, Espírito Santo, Brazil from May to August 2011. RESULTS: In 29 urine samples (96.7%) urinary iodine was above the maximum limit recommended by the World Health Organization (WHO), of 300 mg/L. Fourteen thyroids (25.5%) showed the presence of histological changes compatible with thyroiditis. Higher levels of iodine in urine were observed in females and in of thyroid that showed inflammation (thyroiditis). CONCLUSIONS: We conclude that, in this population, there is excess iodine intake, and greater incidence of inflammatory thyroid disease.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Iodine/urine , Thyroid Gland/pathology , Brazil , Cadaver , Nutritional Status , Sex Factors , Statistics, Nonparametric , Time Factors , Thyroid Diseases/pathology , Thyroid Diseases/urine , Thyroid GlandABSTRACT
PURPOSE: To evaluate the effect of decompression fasciotomy on testes undergoing torsion of the spermatic cord. METHODS: Spermatic cord torsion was induced in 40 Wistar testes for six and 12 hours. At the time of distortion, decompression fasciotomy was performed on half of the animals. After 42 days, the testicles were examined both macroscopically and microscopically. A non-parametric Mann- Whitney U- test was used for statistical analysis. The results were considered significant at p≤0.05. RESULTS: Testicular weight; volume and degree of histological alterations were evaluated. When the groups without and with fasciotomy were compared, a 12-hour torsion subgroup in the fasciotomy group was noted to present larger volume, heavier weight and superior histological classification when compared with the 12-hour subgroup in the without fasciotomy group. No differences between the two groups after six hours of torsion were found. No significant changes were noticed in the contralateral testis. CONCLUSIONS: Testicular fasciotomy (decompression) benefited the macroscopic and histological aspects of the testicles undergoing cord torsion for a 12-hour period. These results demonstrate the role played by compartment syndrome in the pathophysiology of spermatic cord torsion and the need for decompression.