ABSTRACT
OBJECTIVE: To assess if there are changes in brain hemodynamics evaluated by means of transcranial dopplers flow velocity, pulsatile index and cerebral perfusion pressure, between cocaine chronic abusers and healthy volunteers. METHOD: Prospective, case and control, observational study. Sex, age, user history, vital signs and transcranial doppler findings.Statistical analysis was performed by means of normality test, Wilcoxons test for non parametric samples and T Student test. RESULTS: Fifty-three abusers and 35 healthy volunteers were studied. Statistical differences were found for a diminish in age(p=0.008) and cerebral perfusion pressure in all cerebral arteries (pSubject(s)
Cocaine/pharmacology
, Brain/blood supply
, Hemodynamics/drug effects
, Dopamine Uptake Inhibitors/pharmacology
, Cocaine-Related Disorders/physiopathology
, Adolescent
, Adult
, Young Adult
, Chronic Disease
, Prospective Studies
, Case-Control Studies
, Female
, Humans
, Male
, Middle Aged
ABSTRACT
En este artículo se analizan los distintos elementos disponibles para la monitorización del enfermo neurológico crítico. Se actualizan las indicaciones para el monitoreo de presión intracraneana, presión de perfusión cerebral, flujo sanguíneo cerebral, oximetría cerebral invasiva y no invasiva, doppler transcraneano, electroencefalografía, potenciales evocados, presión tisular de oxígeno y microdiálisis cerebral. Las citas bibliográficas permitirán al lector que lo desee profundizar el tema.