ABSTRACT
Guduchi Satva (GS), the starchy material extracted from the Guduchi stem is well-known Ayurvedic single drug formulation having a wide range of therapeutic utility. Species of the plant, stem size, collection time, season and maturity of the plant may affect the yield and physico-chemical profi le of GS. However, published data on such variations is lacking. Considering this, present study is planned to screen seasonal variations in physico-chemical profi le of GS. 18 batches of GS were prepared in six different seasons (3 batches in each season) and fi ndings were systematically recorded. The obtained Satva was further subjected to relevant physico-chemical parameters. Principal component analysis method was adopted to analyze variations. Maximum yield of Satva was obtained in Shishira Ritu (January-February) while the minimum in Grishma (May-June). Variation in taste and color was found in Satva prepared in Varsha Ritu. All functional groups were found to be same in each season. Total alkaloidal contents found bit higher in Varsha and Vasanta. More residual x-variance in alcohol soluble extract and more leverage were observed in water soluble extract due to impact of seasonal spells.