ABSTRACT
In this study, efficacy of two hernia mesh implants viz. conventional Prolene and a novel Prolene-Vicryl composite mesh was assessed for experimental ventral hernia repair in dogs. Twelve healthy mongrel dogs were selected and randomly divided into three groups, A, Band C [n=4]. In all groups, an experimental laparotomy was performed; thereafter, the posterior rectus sheath and peritoneum were sutured together, while, a 5 × 5 cm defect was created in the rectus muscle belly and anterior rectus sheath. For sublay hernioplasty, the hernia mesh [Prolene: group A; Prolene-Vicryl composite mesh: group B], was implanted over the posterior rectus sheath. In group C [control], mesh was not implanted; instead the laparotomy incision was closed after a herniorrhaphy. Postoperative pain, mesh shrinkage and adhesion formation were assessed as short term complications. Post-operatively, pain at surgical site was significantly less [P<0.001] in group B [composite mesh]; mesh shrinkage was also significantly less in group B [21.42%, P<0.05] than in group A [Prolene mesh shrinkage: 58.18%]. Group B [composite mesh] also depicted less than 25% adhesions [Mean +/- SE: 0.75 +/- 0.50 scores, P
ABSTRACT
A retrospective bacteriological study was conducted on 69 irregularly treated patients suffering from chronic suppurative middle ear disease at PAF Hospital, Masroor Karachi. Samples of pus discharge were taken from the external auditory meatus with conventional pus swabs and cultured on blood agar and McConkey's medium. Sixty [87%] samples showed growth within 48 hours. Organisms commonly regarded as pathogens were Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella, Streptococci, Proteus species and lactose fermenting coliform bacteria. Mixed infection was present in 20% of the cases. Gentamicin, tetracycline/doxycycline, chloramphenicol, cephalosporins and quinolones were found to be more effective antimicrobials showing higher sensitivity rate in vitro. Erythromycin showed reasonably good performance in Gram positive cocci