ABSTRACT
To evaluate the prognostic significance of clinicopathological measurement in the diagnosis of acute myocardial infarction [MI] in sheep, acute MI was induced by ligation of left anterior descending coronary artery [LAD]. For this purpose, twenty four healthy sheep were divided into the sham-operated or control group [group I, thoracotomy without MI] and the experimental group [group II, with MI] [n=12 in each], then all animals were subjected to the echocardiographic and clinicopathological analysis 2 days post-MI. Echocardiography revealed significant differences in left ventricular end-diastolic diameter [LVEDD], LV end-systolic diameter [LVESD], LV ejection fraction [LVEF] and LV fractional shortening [LVFS] between groups [P<0.05]. In biochemical analysis, the mean values of troponin [Trop], aspartate aminotransferase [AST] and lactate dehydrogenase [LDH] increased in the MI group compared with the control group [P<0.05]. In conclusion, alterations in echocardiographic and early clinopathological mean values were observed in an ovine model of the experimental acute MI, which could aid researchers in interpreting their results when using this model for MI studies
ABSTRACT
Enzootic calf bronchopneumonia is a multyfactorial disease that occurs in association whit the in telaction of various infectious agenes, and colf susceptibility. The economic losses is associated with death loss and treatment costs, reduction of live weight gain and reduced of productive life span, whith mey be considevable. The aim of this study was to examine the acute phase response in calves with enzootic pneumonia. We measured acute phase proteins [App] and identified some potential markers useful for evaluation of calve's health status. Sixty Holstein calves within two weeks to six months old were divided into two groups. Clinical findings of individual were recorded after the physical examination. Blood samples were taken from the calves and were used for Complete blood count [CBC] and serum biochemical evaluation. Clinical findings including body temperature, pulsation, and respiratory rate were significant between two groups. Hematological parameters showed no significant differences between two groups as well as some biochemical profiles [albumin and globulin]. The results of this study indicated a significant increase in Haptoglobin [Hp] and Fibrinogen [p<0.05]. Our results showed the application of Haptoglobin and fibrinogen measurements as indicators of health in calf herds, thereby facilitating treatment decisions