ABSTRACT
Selenium is an essential trace nutrient for humans and animals. It is required for normal testicular development and spermatogenesis. In the present experimental study, correlations between seminal plasma glutathione peroxidase enzyme activity [as selenium status] and semen parameters are evaluated in 200 males. Semen analysis was performed according to World Health Organization guidelines. Totally, 200 males were subdivided into 5 groups as normospermic, oligospermic, asthenozospermic, azospermic and varicocele groups according to their spermograms. Plasma seminal glutathione peroxidase enzyme activity was determined by Kit [Randox, Germany]. The results showed that glutathione peroxidase enzyme activity is higher in normospermic than oligospermic, asthenozospermic, azospermic and varicocele groups. Meanwhile, there were an inverse significant correlations between glutathione peroxidase enzyme activity and plasma seminal fructose concentration, white blood cell, tail defects of sperm, coiled tail sperms and short tail sperms. On the other hand, the present data showed that there are positive correlations between vitality, sperm count, motility and normal morphology. The present study indicated that measurement of glutathione peroxidase enzyme activity as selenium status could be a good marker for evaluation of male infertility