ABSTRACT
Background and Objective: Varicella zoster virus [VZV] can cause a moderate disease in children, but with high risk of serious disease or death in children with acute lymphoblastic leukemia [ALL] Vaccination from infection can be safe, immunogenic, and effective in children with leukemia. This study was done to evaluate the IgG and IgM antibodies against VZV in children with acute lymphoblastic leukemia
Methods: The descriptive-analytic study was performed on 66 children who were on chemotherapy in Dr Shigh hospital in Mashhad, Iran during 2012. Patients were receivied VZV vaccine. The title negative or positive serum sample for IgG-anti-VZV avidity was determined by using a test kit before and after injection of vaccines VZV for considering the efficacy of vaccines on pediatric patients
Results: Title serum sample IgG were positive in 32.6% patients, these children have history of chicken pox disease and to be safe against of VZV. 78.3% of the patients were negative for IgG antibody and sensitive against of VZV
Conclusion: Children with ALL receiving chemotherapy are sensitive to chicken pox disease according to negative IgG titer against VZV
ABSTRACT
Introduction: About 20-40% of people with diabetes experience varying levels of distress and general symptoms of anxiety and depression. This study aimed to evaluate the effects of mindfulness-based stress reduction group training on depression, anxiety, stress, self-confidence and hemoglobin A1c in young women with type 2 diabetes
Materials and Methods:In this pretestposttest- control group design study, we used instruments such as demographic data and depression, anxiety and stress [DASS-21] and the Rosenberg self-confidence questionnaires. The study population included 60 patients with diabetes randomly divided into 2, the experimental and control groups. The experimental group received the mindfulness intervention with 8 sessions each 2.5 hours while the control group received no intervention. Following this, during the ninth, session both groups again completed the questionnaires
Results: Patients in experimental group reported lower levels intensity of anxiety, stress and HbA1C, but higher self-confidence in comparison to the controls after intervention [P<0.05], although differences in levels of the depression variable between two groups was not significant. In addition, between HbA1c and all variables, [depression, stress, self-confidence] significant correlations were observed
Conclusion: Results suggest that depression, anxiety, stress and self- confidence are associated with HbA1C level and a mindfulness-based stress reduction program can be effective in reducing the psychological symptoms in these patients, leading to increased confidence and improved glycemic control in women with type 2 diabetes