[Cardiovascular retention of drepanocytosis]

Sickle cell disease is an autosomal recessive genetic disease characterized by the formation of abnormal hemoglobin S [HbS]. There are several forms of sickle cell disease: SS homozygous, heterozygous and thalassemic. Cardiovascular complications are increasingly evident; this is related to the increased life expectancy of patients with hemoglobinopathies: rhythm and conduction disorders, heart failure and pulmonary artery hypertension. These cardiovascular complications represent the major prognostic factor of sickle cell disease. Through this review of the literature we will describe the clinical and paraclinical aspects of cardiac involvement during sickle cell anemia

[Kidney disease in high hypertension]

The relation between hypertension and kidney disease is difficult to distinguish if the kidney disease is the cause or the consequence of hypertension or there is an other factor responsible. The aim of this study is to analyse the different kidneys damage in a group of hypertensive outpatients. It's a prospective study including 185 patients. The OMS criteria were necessary to have a confirmation of hypertension. The check up contained "azotaemia, creatininaemia, kaliaemia, natriaemea, alburninuria ". All the patients had a kidney ultrasonography. This study included l46females and 39 males. The average age was 48 years. Most of the patients [43%] were aged from 50 to 60 years. Kidney damage was found in 56 cases. There are 2 types of kidney disease in hypertension. The malignant nephroangiosclerosis found in accelerated hypertension and glomerulo-sclerosis with slow evolution noted in moderated hyper-tension and diabetes. Even though a benign kidney disease may be found in a hypertension and patient, it may be a sign of more important vascular and kidney risk and justifies vigilant surveillance

[Dilated cardiomyopathy in appearance primitive. about children [23 cases]]

It's a retrospective study of 23 cases of dilated cardiomyopathy in the child collected in different services of pediatrics [Ibn Rochd CHU and Sid Soufi] and in the Cardiology service of the Ibn Rochd CHU on a period of 8 years [1981 -1988]. The analysis of thee observations showed that: - The CMD of the child is a relatively rare affection - The middle age is of 3,8 years. 82,4% are young children of less than 6 years old, - The sharing is homogenous between the two sexes. - The family inquiry is imperative during all CMD of primitive behaviour. - The clinic board is that of a cardiac insufficiency [95,6%], the most often dramatic In the infant. - The electrocardiogram is constantly disturbed, but without any specificity for the cardiomyopathy. - The echocardiography is apriviled ged technique for the study of the dilated cardiornyopathies. It allows to set the diagnosis, to follow the evolution and to value the prognostic. - The medical treatment is based on the association of a rest, a salt-free diet, diuretics and digitalics. - The evolution is marked by a strong precocious mortality with possibility of a total recovery in almost a the cases. The etiology remains unknown and the prognostic stays difficult to value