ABSTRACT
We determined the prevalence of congenital hypothyroidism and the rate of consanguinity among parents of hypothyroid neonates among 93 381 neonates born in 17 hospitals in Isfahan from May 2002 to April 2005. Serum thyroxine [T4] and thyroid stimulating hormone [TSH] levels were measured on the 3rd-7th day of birth and neonates with abnormal levels were recalled and the levels reassessed. Those with TSH
Subject(s)
Female , Humans , Male , Consanguinity , Gene Frequency , Infant, NewbornABSTRACT
Background: Haemophilus influenza [HI] is the most commonly found pathogenic bacteria in pediatric otitis media and lower respiratory tract infections. Bacterial attachment to pharyngeal cells and proliferation may be necessary for infection. In the presence of human milk, attachment of HI to pharyngeal cells and colonization may be inhibited. To evaluate the protecting role of breast milk, we investigated the incidence of HI isolated from the throat of healthy infants with different feeding methods
Methods: between August 2002 and March 2003, 210 healthy infants [70 purely breast-fed, 70 purely formula-fed, 70 mixed-fed], aged 1-6 months were enrolled into the study and a throat culture was taken in all of them. The incidence of HI was evaluated using Haemophilus Test Agar Bose [HTAB] plates
Results: the incidence of HI in purely breast-fed, mixed-fed and purely formula-fed infants was 2.9%, 42.9% and 75.7% respectively [P = 0.000]. The mean age and weight of cases in the three groups were not statistically different
Conclusion: these data suggest that human milk protects the throat of healthy infants from HI colonization especially in purely breast-fed cases
ABSTRACT
Background: adequate hydration and good urine output improve the efficacy of phototherapy. The aim of this study was to evaluate the effect of intravenous fluid supplementation on decrease of serum bilirubin levels in jaundiced healthy term infants during conventional phototherapy
Methods: sixty healthy breast-fed neonates with non-hemolytic hyperbilirubinemia were assigned randomly to receive either breast milk exclusively [non-supplemented group; n=30] or intravenous fluid in addition to breast milk [supplemented group; n=30] during conventional phototherapy
Results: the mean total serum bilirubin [TSB] levels at the time of enrollment and within 84 hours after phototherapy were not statistically different between two groups. Similarly, the mean rate of decrease in TSB levels during the first 12 h of phototherapy were 0.13+/-0.06 and 0.10 +/- 0.1 mg/dL/h in supplemented and non supplemented groups , respectively [P=0.13]. Duration of phototherapy required in supplemented and non-supplemented groups was 58 +/- 13.02 and 63.20 +/- 13.71 hours, respectively [P=0.13]
Conclusion: these data show that administration of extra intravenous fluid in jaundiced healthy, term, breastfed neonates have no beneficial effect on the rate of serum bilirubin reduction during conventional phototherapy