ABSTRACT
Giant hypertrophic gastritis or Menetrier's disease is a rare gastric lesion involving the entire stomach or part thereof and is characterized by marked enlargement of the gastric mucosal folds [1, 2]. In 1888 Menetrier [3] first described this entity of excessive proliferation of gastric mucosal cells with thickening of the gastric wall. In his original paper he described two types: the first called "Polyadenoma Polypeux", now called "Diffuse adenomatosis", and the second called "Polyadenome en nappe". Currently giant hypertrophy of gastric mucosa in association with a protein-losing enteropathy is generally referred to as Menetrier's disease, Although it was described as early as 1888 [3], only 200 cases have so far been reported in the literature [4]