ABSTRACT
Tongue cancer is one of the most common cancers of the oral cavity, excluding lip, and the median age of the patients is approximately 60 years. Treatment results of a total of 110 patients with oral tongue cancer admitted to cancer Institute of Tehran University between 1999-2003 were retrospectively analyzed. The patients were treated by surgery or radiotherapy or chemotherapy in a curative setting. The median age at the time of first visit was 67 years [range 27- 91years].51 patients [46.4%] were female and 59 [53.6%] were male. Primary treatment was surgery in 86 patients [78.2%], radiotherapy alone in 12 patients [10.9%], chemo radiation in 3 patients [2.7%] and chemotherapy [as neo adjuvant therapy] in 8 patients [7.3%]. Median dose of radiation in patients who received radiotherapy was 6000CGY in the range of [5000-7500 CGY]. Median of follow-up of patients was 10 months in range of [1-78] months. Local and loco-regional recurrence remains a major clinical problem in oral cavity tumors. Additional studies and detailed analysis of the selection criteria and treatment outcomes across trials are needed to define the best treatment modalities