Antibacterial and antifungal studies of various extracts of indigofera aspalathoides root

Five different crude extracts: petroleum ether, chloroform, ethyl acetate, ethanol and aqueous extract of Indigofera aspalathoides have been studied for both in vitro antibacterial and antifungal activities. The different extracts showed remarkable inhibitory action against various gram positive and gram negative bacteria and two fungal species

Anti-hyperglycemic activity of ethanol leaf extract of marsilea quadrifolia linn

TheplantMarsileaquadrifoliaLinn. [Marsileaceae] has been screened for its hypoglycemic activity in both normal and alloxan-induced diabetic male albino mice. In the present study, the vacuum dried ethanol extract of leaves of Marsilea quadrifolia showed significant hypoglycemic activity. The mice were randomly divided into two main groups. The Group I animals were injected with alloxan mono-hydrate at a dose level of 150mg/kg body weight intraperitoneally. Group II animals were used as normal [nondiabetic]. The diabetic and nondiabetic animals were divided into four sub groups. Mice in first group received 1% CMC, second group received a suspension of the ethanol extract at a dose level of 500 mg/kg and third group was administered with Glibenclamide. The mean glucose levels of mice at various time intervals were observed. The ethanolic extract of M. quadrifolia is endowed with significant anti-hyperglycemic activity thereby justifying its use in the indigenous system of the medicine

In vitro and In vivo antisnake venom activity of Coccinia indica L. Leaf

In vitro and in vivo antisnake venom activity of the ethanolic and aqueous extracts of the shade dried leaves of Coccinia indica L.was studied through inhibition of in vitro HRBC lysis and using albino mice in modifying the lethal effect of the test dose of Naja naja venom. The effectiveness of these two extracts were evaluated by i.p administration at two different dose levels five minutes after administration of the snake venom. The LD50 of Naja naja venom was found to be 16 µg/20g body weight. The ethanolic extract of the leaves of C. indica markedly decreased the percentagelmortality in venom induced toxicity in mice at dose level 750mg/kg body weight. The ethanolic extract of C. indica is endowed with significant antisnake venom activity thereby justifying its use in the indigenous system of the medicine