Cutaneous leishmaniasis in Multan: Species identification

To identify the Leishmania species being responsible for cutaneous leishmaniasis in Multan. Parasites were isolated from clinically and parasitologically confirmed lesions of cutaneous leishmaniasis from 30 patients by fine needle aspiration [FNA]. The bioptical materials were then cultured in Evans Tobie's medium and parasites isolated were identified by isoenzyme electrophoresis technique. Successful Leishmania isolates were obtained from 16 patients. All strains were identified by biochemical techniques as belonging to Leishmania tropica zimodeme MON7 variant PGD. The causative species was identified as Leishmania tropica

Giant hypertrophic gastropathy [Menetrier's disease] with bleeding peptic ulcer

Giant hypertrophic gastritis or Menetrier's disease is a rare gastric lesion involving the entire stomach or part thereof and is characterized by marked enlargement of the gastric mucosal folds [1, 2]. In 1888 Menetrier [3] first described this entity of excessive proliferation of gastric mucosal cells with thickening of the gastric wall. In his original paper he described two types: the first called "Polyadenoma Polypeux", now called "Diffuse adenomatosis", and the second called "Polyadenome en nappe". Currently giant hypertrophy of gastric mucosa in association with a protein-losing enteropathy is generally referred to as Menetrier's disease, Although it was described as early as 1888 [3], only 200 cases have so far been reported in the literature [4]