ABSTRACT
Background: To evaluate the value of diffusion weighted magnetic resonance imaging [DWMRI] in detection and T- staging of bladder carcinoma and correlation with histopathological staging
Patients and Methods: An analytic prospective study was conducted at the MRI units of Al-yarmook teaching hospital in the period from January of 2015 to December 2015, 42patients [36 male and 6 female] presented with hematuria [40 patients] and 2 patients presented with pelvic pain were enrolled prospectively, they underwent conventional magnetic imaging [MRI] and diffusion weighted MRI using 3 tesla MR units [Achieva; Philips medical systems, the Netherlands]. Diffusion weighted images were obtained using a single shot echo planar imaging sequence EPI with b value 0,500 sec/mm [2]. ADC value map was reconstructed and mean ADC value were measured in 42 patients .and histological examination was done to all patients
Results: Correlation between standard MR staging of bladder carcinoma and histopathological results revealed that 17 patients [40%] had the same T -staging while 17 patients [40%] over staged. DWI and ADC values were able to declare the cause of overstating by discrimination between tumoral tissue and peritumoral inflammation. Statistically significant difference is found between ADC value of bladder tumor and those of urine
Conclusion: Diffusion weighted MR imaging at 3 tesla is new and good imaging modalities for detection and staging of bladder carcinoma, without using contrast media, so can used in patient with renal impairment or contrast media allergy