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1.
Southeast Asian J Trop Med Public Health ; 1996 Jun; 27(2): 319-24
Article in English | IMSEAR | ID: sea-32749

ABSTRACT

In vitro sensitivity of Acanthamoeba castellani was tested to three drugs: Chloroquine, ivermectin and fungizone (amphotericin B). Sensitivity was demonstrated to the latter two compounds but not to chloroquine. Thus ivermectin and amphotericin B show promise as therapeutic agents against this parasite.


Subject(s)
Acanthamoeba/classification , Amebicides/pharmacology , Amphotericin B/pharmacology , Animals , Anti-Bacterial Agents/pharmacology , Chloroquine/pharmacology , Drug Evaluation, Preclinical , Drug Resistance , Ivermectin/pharmacology , Time Factors
2.
Southeast Asian J Trop Med Public Health ; 1994 Sep; 25(3): 485-9
Article in English | IMSEAR | ID: sea-36151

ABSTRACT

The distribution of anti-toxoplasma antibodies among the aborigines in Malaysia and its association with other soil transmitted infections and eosinophilia were studied. A total of 415 serum samples were collected and tested by IFA test. Overall prevalence was 10.6%, lower than previously reported. The antibody titers showed a unimodal distribution peaking at 1:8 dilution. There was a higher proportion of high antibody titer (> 1:128) in the adult compared to the children with no significant difference in prevalence rate by sex. The pattern of infection does not differ from other soil transmitted infections and there was no association between raised Toxoplasma antibodies with eosinophilia.


Subject(s)
Adolescent , Adult , Age Factors , Animals , Antibodies, Protozoan/analysis , Child , Child, Preschool , Racial Groups , Eosinophilia/complications , Humans , Infant , Malaysia/epidemiology , Middle Aged , Native Hawaiian or Other Pacific Islander , Prevalence , Seroepidemiologic Studies , Toxoplasma/immunology , Toxoplasmosis/complications
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