Frequency and type of stroke in hypertensive patients

To describe the frequency and type of stroke in hypertensive patients Descriptive study. This study was conducted in the carried out in the Department of Medicine [ICU] at Peoples Medical College / Hospital Nawabshah, from 1[st] September 2008 to 28th February 2009. A total of 100 patients were admitted to the ICU of medicine department. Relevant investigations like CT Scan brain, ECG and routine investigations like blood CP, Serum cholesterol and random blood sugar were done. Data was retrieved from the files on a structured performa. 65 were male and 35 female with ratio of 1.8:1. Mean age was 60.58 +/- 4.25 years for male and 59.22 +/- 3.25 for female. Ischemic stroke were 73% cases while 27% cases were recurrent hemorrhagic stroke. In ischemic stroke uncrossed hemiplegia occurred in 69[94.5%] cases and crossed hemiplegia occurred in 4[5.5%] cases while all hemorrhagic stroke patients suffered from uncrossed hemiplegia [100%]. Frequency of ischemic stroke was more common then hemorrhagic stroke in hypertensive patients

Frequency of hyperuricemia in patients with ischemic heart disease

To determine the frequency of hyperuricemia, as a risk factor, in patients with ischemic heart disease in our setup. This prospective and observational study was carried out in the Departments of cardiology, medical unit III and pathology, Peoples Medical College and Hospital, Nawabshah from 15[th] January 2007 to 15[th] July 2007. Fifty patients, of any age and of either sex, diagnosed on ECG as ischemic heart disease [IHD] were selected and compared with serum uric acid [SUA] levels and age, sex, approximately body mass index [BMI] matched healthy controls. SUA was measured on 3[rd] day of admission by using enzyme uricase method on CLINIKON photometer 5010. Hyperuricemia was found in 27 out of 50 IHD patients and in 5 out of 50 controls; therefore a highly significant association was observed. Mean SUA level was 7.21 +/- 2.14 in patients with ischemic heart disease and 5.38 +/- 1.26 was found in healthy control subject. The difference between these two means was highly significant [P<0.0001]. Hyperuncemia significantly associates with IHD. It does not cause t IHD, neither is an independent risk factor but it only accelerates the process of atherosclerosis which can worsen the preexisting IHD

Experience with spinal instrumentation for tuberculosis spine at PMCH Nawabshah

Spinal column is the common site of skeletal tuberculosis. Anteriorly there are three varieties: Paradiscal, Centrosomatic and Anterior Longitudinal. Extra-osseous involvement causes paravertebral abscess, epidural abscess or involvement of ligaments. The purpose of this study is to identify the frequency, presenting features, diagnostic tests and outcome of decompression and stabilization of tuberculous spondylitis. This study was conducted in Peoples Medical College, Nawabshah. All cases of spinal tuberculosis treated surgically were included. Admission criteria for these patients were advanced form of spinal tuberculosis, presenting with progressive deformity, neurological deficit, intractable pain, large paraspinal abscess or posterior element involvement. Over a period of 5 years, we had operated upon 248 cases of tuberculous spondylitis. Females dominated [1.91 times]. Bulk of series belonged to younger age group less than 40 years. Majorities of them had pain, neurological deficit and gibbus deformity. Surgery was performed to decompress the cord, apply a bony strut graft and stabilize with instrumentation. Thoracic region was commonly involved. Anterior approach was preferred because most of times anterior elements were involved. Webb Morley instrumentation system was used in majority of cases from D4 to L4. At the end of 6 months postoperatively pain relief was observed in 94.9% and neurological [motor] improvement in 92.2% cases. In this series we have observed that in our part of the world tuberculosis of spine is commonly seen in females and younger age group. Anterior decompression and stabilization is helpful in segmental rigid fixation of spine, pain relief deformity correction and early neurological recovery