ABSTRACT
Nuclear DNA content of laryngeal epithelial cells in smears was carried out by DNA cytometry with automatic microscope and T.V., image analysis system in 6 adult papilloma and 10 keratosis of the larynx patients. The method had high degree of precision confirmed by whole tissue biopsy and serial sections. The method is non invasive and allows fair diagnosis of suspicious and early malignant cases
Subject(s)
Humans , DNAABSTRACT
Zoonotic cutaneous leishmaniasis caused by L. major and toxoplasmosis caused by T. gondii are prevalent among man and animals in several localities in Egypt particularly in the Nile Delta and Sinai. Double infection may take place. In this paper, it was intended to study the concomitant infection in albino mice. The results showed that the clinical and histopathological pictures differ in concomitant infection from that shown by infection with either parasite alone. Therefore leishmaniasis and toxoplasmosis must be diagnosed parasitologically
Subject(s)
Toxoplasmosis , MiceABSTRACT
Seven cases of monomorphic basal cell adenomas of salivary glands were studied with light microscope and immunocyto-histochemically. On the basis of immunocyto-histochemical findings using four different antibodies [EMA, SIOO protein, CAM 5.2 and secretory component], it was concluded that this tumor originates from undifferentiated stem cell analogous to the cells seen at the end bud stage of salivary gland embryomorphogenesis prior to cytodifferentiation and functional maturation into secretory and myoepithelial cells, such undifferentiated stem reside as "reserve cells" in the intercalated ducts of fully developed salivary gland, also the myoepithelial cells play little role in histogenesis of this tumor
Subject(s)
Humans , ImmunohistochemistryABSTRACT
Visceral leishmaniasis [V.L.] is a known human disease in the Middle East. In this study, the correlation between the clinical manifestations and the different immunological, pathological and parasitological pictures of the disease were studied. It was concluded that V.L. is characterized by splenomegaly, irregular pyrexia and cachexia. Besides, palpable liver, purpuric rash, edema, jaundice, night sweats and dysentery occur. Anaemia is invariable may be severe and can occur early. The blood picture shows leucopinea and relative lymphocytosis. Leishmanin skin test indicates failure in cell-mediated response. The IgG greatly increase than the IgM. Liver biopsies show variable picture, but detection of amastigotes are not easily. The bone marrow smear is a safe and dependable method of diagnosis