ABSTRACT
Hodgkin Lymphoma [HL] is a lymphoid tumour that represents about 1% of all neoplasms occurring worldwide. HL is the most treatable of childhood malignancies. The etiology of HL is unknown. However, increase risk has been reported in males, with autoimmune diseases, poor socioeconomic status, increased family size, Ebstein Barr Virus [EBV] exposure, congenital or acquired immunodeficiency and those with a family history of HL. Familial HL is rare. The risk of developing HL is increased six times in the siblings of the affected patients. Both genetic and environmental factors have been postulated in the pathogenesis. No case of familial HL has been reported in the literature from Pakistan. We report two families with familial HL occurring in siblings that have been successfully treated and are on our follow-up