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Background: Hyponatremia is one of the most common laboratory dispute which may occur in many clinical conditions. Hyponatremia complication may include significant co-morbidities like heart failure, liver cirrhosis, and nephrotic syndrome in addition to diuretic use.Material & Methods:This study was a retrospective cross-sectional study, conducted at the department of Medicine in Tairunnessa Memorial Medical College. The study was conducted during the period ofJanuary 2019- April 2022. The total sample size for this study was 94.Results:Most patients 24(25.5%) were aged between 41-50 years and followed by 5(5.3%) were aged 11-20 years. Most of the respondents 65(69%) were female and 29(31%) were male. Most of the respondents 49(52.1%) were housewife. Diarrhoea was seen in 50(53.2%) cases and followed by vomiting in 27(28.7%), nausea in 15(16%), general weakness in 10(10.6%), anorexia in 41(43.6%). HTN&BA, DM, CKD in 6(6.4%), severe pre eclampsia in 3(3.2%), chronic kidney disease in 2(2.1%), COPD in 2(2.1%). Hyponatremia was found mild in 68(72.3%) cases, moderate in 24(25.5%) cases and severe in 2(2.1%) cases and followed by Hypokalaemia (K+ <3.6 mmol/l) was found in 59(62.8%), normal K+ level in 31(33%) cases and mild-moderate hyperkalaemia in 3(3.2%) cases. Hypochloridaemia (Cl– <96 mmol/l) was found in 62(66%), normal Cl– level in 29(30.9%) cases andhyperchloridaemia in 3(3.2%) cases. Tab. Nacl was prescribed to 67(71.3%) patients, normal saline to 79(84%), Hypertonic saline (3% Nacl saline) to 5(5.3%), Cholera Saline to 3(3.2%) and others suggestion along with prescribed medicine was given to 94(100%) patients.Conclusions:Hyponatremia is one of the common electrolyte abnormalities which can be seen among hospitalized patients. It is mostly seen in elderly and critically ill patients who are admitted to the ICU.
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Background: Urinary tract infections (UTIs) are considered to be the chronic public health problem due to morbidity and financial cost as urological diseases causes the highest health care cost. UTI is known as one of the most common diseases today. UTI can occur in both men and women, but studies found that the incidence of UTI is more common in women especially among the sexually active women. Material & Methods:This study was a retrospective cross-sectional study which was conducted at the department of Medicine in Tairunnessa Memorial Medical College and Hospital, Gazipur, obstetrics and gynecology in Bikrampur Bhuiya Medical College and Hospital, Munshiganj and Medicine in City Medical College and Hospital, Gazipur. The study was conducted during the period of February 2018- January 2022. The total sample size for this study was 131.Results:Most of the respondents 56(42.7%) were aged from 26-35 years. Majority of them 117(89%) were female whereas only 14(11%) were male. Burning sensation of micturition was found in 115 patients where 46(40%) had burning for 0-3 days, 63(54.8%) for 4-7 days and 6(5.2%) for >7 days. In most cases causative organism was E. Coli in this study. According to sensitivity patterns of E. Coli Amoxiclav was used in 77(59%) cases and followed by Amikacin in 94(72%), Azithromycin in 120(92%), Cefixime in 130(99.2%), Ceftriaxone in 83(63.3%), Cefuroxime in 37(28.2%), Imipenem in 62(47%), Ciprofloxacine 64(49%), and Gentamicin in 38(29%) cases. In assessing the antibiotic resistance pattern of E. coli Ampicillin was used in 55(42%) cases and followed by Amoxycillin in 98(75%), Colchicine in 13(10%), Linezolid in 35(26.2%), Amoxiclav in 54(41.2%), Colistin in 16(12.2%), Imipenem in 69(53%) and Novobiocin in 62(47%) cases.Conclusions:Antibiotics are considered to be the only treatment for UTI. But antibiotic resistance is highly prevalent in bacterial isolates around the world, especially in developing countries.
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Background: Fractures of the tibial shaft are important for tworeasons. The first is that they are common, the second is thatthey are controversial - and anything that is both common andcontroversial must be important. Fractures of the shaft of thetibia cannot be treated by following simple sets of rules.Because of its location tibia is exposed to frequent injury and itis the most commonly fractured long bone.Objective: To evaluate the treatment of open tibial shaftfracture of Gustilo IIIA grade by Trans osseous osteosynthesistechnique with Illizarov External Fixator as a primary anddefinite mode of treatment.Methods: Clinical trial (Quasi Experimental study) fromJanuary 2009 to June 2010 (18 months) at National Institute ofTraumatology and Orthopaedic Rehabilitation Purposivesampling was done according to availability of the patients andstrictly considering the inclusion and exclusion criteria andsample size was 17 no of cases.Results: 14 male and 1 female patient between 17 and 51years were studied. Most common age group in this serieswere 26-35 year age group ((53.33%) and average age of thepatients was 30 years with SD of ±8.67. Most of the patientswere male and road traffic accident was the leading cause ofinjury (70.58%). Left side involved in (58.82%) most of thecases and 2 patients had bilateral fractures. Commonest site ofthe fractures were middle third (58.82%) of the tibia. Most ofthe fractures were comminuted type of fractures (47.05%).Most of the patients were operated on the day of admissionand in some cases within 4 - 7 days of admission. Averageduration of hospital stay was 8.06 days ranging from 1 day to28 days. Total duration of treatment was average 186.66 days(26 weeks) highest 291 days (42 weeks) and lowest 140 days(20 weeks). Most of the patient had soft tissue healing bygranulation tissue formation (35.29%). Others were treated byprimary closure, Delayed primary closure, secondary closure,partial thickness skin grafting.Conclusion: In this study the results of open tibia fracture(Gustilo IIIA) by Transosseous osteosynthesis technique withIlizarov External Fixator has been found to be satisfactory.Though there were a few minor complications with the fixatorthe dynamisation and compressing ability of this stable frameprovided good union without any second surgical procedure orbone grafting and prevented any malunion.
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This was a clinical trial (quasi experimental) study carried outat the National Institute of Traumatology and OrthopedicRehabilitation (NITOR), Dhaka, between July 2004 to June2006, involving 16 patients with habitual dislocation of thepatella. All these cases were managed by Madigan operativeprocedure. Aim of this study was to evaluate the effectivenessof the madigan procedure in the treatment of habitualdislocation of the patella. Out of these 16 patients 2 weresubsequently lost from follow up. So, the study finally consistedof 14 patients. In this study non-random purposive techniqueas per inclusion and exclusion criteria was followed irrespectiveof sex. Most common age group in this study was 6-10 years(62.5%). The mean age of occurrence was 8.25 years.Repeated intramuscular injection on the thigh was thecommonest cause of dislocation found in 37.5% cases. Thesecond most common cause of dislocation was history of boil.Abscess or cellulitis on the thigh followed by contracture of thequadriceps muscles. Various postoperative complications likehypertrophic scar constituted (18.75%), stitch granuloma(6.25%), restriction of knee motion (6.25%) and re-dislocationoccurred in (6.25%) cases. Functional outcome in themanagement of habitual dislocation of the patella wasanalyzed by using the Hospital for Special Surgery (HSS) kneescore. Regarding the final or overall results in this series, therewere 71.43% cases were found satisfactory and the remaining28-57% were found unsatisfactory result.
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Objective: In this study our main aim to evaluate the outcomeof primary rigid internal fixation of displaced fracture neck ofthe femur with muscle pedicle bone graft in young adult.Methodology: This prospective observational study wasconducted at National institute of traumatology and orthopaedicrehabilitation (NITOR), Dhaka from July 2003 to June 2005.During the study, recent neck femur fracture 12 cases, inbetween age 20-55 years irrespective of gender were taken asa sample.Results: In the experiment, 75% were male patient and 25%were female patients. 66.67 % patients with type 1V fractureand 33.33% patients were with type III fracture. Also, after thetreatment. 83.33 % patients obtained satisfactory result and16.67% was unsatisfactory.Conclusion: From our study we can conclude that thistechnique is especially applicable in early days of fracture toachieve union and revisualization of the proximal fracturefragment and prevent non-union or avascular necrosis. Thefollow up period of this initial study is short, long-term follow upand evolution of the viability of this procedure should provideadditional useful result.
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Objective: The present study was designed to investigate antioxidant and cytotoxic effects of the methanol extract of Circuligo recurvate leaves, which belongs to the family Hypoxidaceae, the primary phytochemical property was also intended to screen out. Methods: The antioxidant activity of the extracts were studied using 1,1-diphenyl-2-picryl hydroxyl (DPPH) radical scavenging activity, reducing power capacity assessment and results obtained were compared to standards. The total phenolic contents and flavonoid contents were estimated from Gallic acid and Quercetine calibration curve respectably. Results: IC50 value of the extract showed 259.040±3.98 μg/mL in case of the DPPH scavenging assay, the total phenolic and the flavonoid contents of extract was 384±3.34 mg/gm and 149.23±1.12 mg/gm respectively. The reducing power capacity of the extract observed to raise as the concentration of the extract gradually increases. The mortality rate at the assessment of cytotoxicity in brine shrimp napulii model was found increasing with the increase of the concentration and the LC50 value of extract was 164.58±2.67 μg/ml. Conclusion: These findings demonstrate that the leaves extract of C. recurvata has the presence of antioxidant compound and there is presence of molecules that can inhibit rapid growing cells.
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Background: The word asphyxia is now commonly used to describe a range of conditions for which the lack of oxygen whether it is partial (hypoxia) or complete (anoxia) is considered to be the cause. The cardinal signs of asphyxia are cyanosis, congestion and petechial haemorrhage. Objective: To investigate the causes and manner of asphyxial death. Materials and Methods: It was a retrospective study conducted in the department of Forensic Medicine, Dinajpur Medical College, Dinajpur during July 2004 to June 2006. A total of 96 cases were examined and recorded. These cases were brought to the morgue of Dinajpur Medical College from 13 different police stations and 1 railway GRP station of Dinajpur district. The data were collected from the autopsy reports (preserved third copy) with permission of the concerned autopsy surgeons. Results: 88.55% of asphyxia deaths were due to hanging, 6.25% due to strangulation and 5.20% were due to suffocation. Conclusion: Most of the asphyxial deaths are due to hanging.
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Background: Back pain and sciatica are very common in adult persons. These cause a great loss of working hours with financial loss of individual and the nation. Very careful evaluation must be done to treat these patients. Injudicious treatment, whether medical or surgical, may aggravate the sufferings. Objective: To study immediate and long term effect of the prolapsed intervertebral disc surgery. Materials and Methods: This observational study was done in Enam Medical College & Hospital, Savar, Dhaka during January 2007 to June 2011. Sixty four patients operated during this period for prolapsed lumbar intervertebral disc were included in the study. Fifty six (88%) were male and 8 (12%) were female. Age range was 30 to 50 years. Most of the patients presented with back pain and sciatica with no definite history of trauma or weight lifting. Diagnosis was confirmed by MRI. Results: Sixty (94%) patients had no pain after surgery and only 4 patients had occasional pain. Conclusion: Maintenance of strict criteria for the surgery yields very good result.
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Background: Diclofenac sodium is a non-steroidal anti-inflammatory drug with reportedly undesirable harmful side effects including blood disorders, abdominal pain, ulceration and bleeding of the stomach or intestine. Objective:The present study was conducted to investigate the effect of diclofenac sodium on erythropoiesis, on stomach and liver under different conditions. Method: This experimental study on animal model was conducted in the Department of Physiology, Bangladesh Agricultural University, Mymensingh, between July and August 2007. A total of 45 Swiss Albino mice were randomly assigned into five equal groups (n=9) and they all were fed with standard broiler pellet (25 gm/mice/day) throughout the experimental period of 40 days. Keeping 1 group as control(groupA), 4 groups were treated with diclofenac sodium @ 3 mg/kg body weight (bwt) orally in empty (group B)or full stomach with (group c) or without vitamin B12(group D) @ 10 μg/Kg body weight through intramuscular route. Total erythrocyte count (TEC) and Hb% was determined to assess erythropoiesis. Macroscopic and microscopic changes of liver and stomach were studied by standard laboratory method. Data were analyzed statistically by ANOVA and un paired t test. Result: Oral administration of this drug significantly (p<0.01) decreased Total Erythrocyte Count(TEC) and Hb in the animals treated with diclofenac sodium in empty stomach and in the animals treated with diclofenac sodium plus vitamin B12 in empty stomach. All the treated mice showed slight to moderate congestion of the gastric mucosa and liver. Conclusion: Intake of diclofenac sodium in empty stomach may produce harmful side effect on stomach and liver.
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The purpose of this study was to assess the duration of breastfeeding and the sociodemographic factors affecting it. Data for the study were drawn from the Bangladesh Demographic and Health Survey 2004. In total 5,364 mothers were included in the study. The life table and Cox’s proportional hazards model were employed for the analysis of breastfeeding-related data, which showed that the average duration of breastfeeding was 31.9 months. Cox regression analysis revealed that the duration of breastfeeding was positively associated with maternal age, contraceptive-use, work status, and religion and was negatively associated with age at marriage, parity, delivery status, region, and maternal education. Younger mothers, having higher education, higher maternal parity, caesarean-section birth, being a Muslim, and mothers who have not used any contraceptive were associated with lower duration of breastfeeding. The findings suggest that health institutions can play a significant role in promoting breastfeeding in Bangladesh. Educational campaigns that stress the benefits of lactation are important strategies for encouraging mothers to breastfeed longer.