Effect of Shatavari Root Powder (Asparagus racemosus) Supplementation on Milk Composition of Sahiwal Crossbred Cows

The present investigation was conducted to assess the effect of Shatavari root powder (Asparagus racemosus) supplementation on milk composition of Sahiwal crossbred cows during summer season on twenty lactating Sahiwal crossbred (H.F. × Sahiwal) cows in early stage of lactation were selected for the experiment. All the cows were randomly divided into two groups T1 (control) and T2 (Treatment) of 10 in each group. The treatment group was provided Shatavari root powder @ 50 g/head/day for 90 days post partum. Data related to milk composition takes fortnightly interval. The overall average milk fat, Protein and Lactose percent during the experimental period in T1 and T2 groups were 3.77 ± 0.01, 3.84 ± 0.03, 3.43 ± 0.01 and 3.46 ± 0.01, 4.54 ± 0.06 and 4.69 ± 0.06 percent respectively, there was no significant (P<0.05) differences between T1 and T2 groups. The overall average solid not fat (values) and total solid (values) differed significantly (P<0.05) between T1 and T2 groups 8.84 ± 0.04, 9.11 ± 0.11, 12.66 ± 0.03 and 13.02 ± 0.14% in T1 and T2 groups was significantly (P<0.05)

Soul and Mind as Functional Control in the Management of Human Body: A Scientific Approach

Soul is an eternal, noble and everlasting presence of energy in human body, represents bestcreation of nature. The combination of five dhatus (Air, Water, Earth, Agni, Akasha) with Soul is called‘Shad Dhatu’ purusha. When the Soul leaves the body, all biological and physiological activities are notfunctional and body declared as dead body. The sharira (body), indriya (sense organs), Mann (mind),and Soul (atma) are connected together in the living human body, this is called as Ayu (life). Mann,Soul, and Sharira are just like the tri-unity. The world is self-sustained by their combination and theyconstitute the sol stratum for physical, mental, psychological activities along with spiritual knowledgegrowth in human life. The soul is non-physical and non-materials. Science does all experiments forconfirming and understanding the events and action. This initiate an effort to provide and develop aconcept to hypothesize this relationship among Soul, Mann and body. They all are connected togetherand cannot be separated till death. The separation mechanism is not clearly understood for theirinternal survival in the human body and even after death also. We never find any kind of method,techniques and technology to identify soul and mann individually in the living body even after death.The whole body functions and their operational mechanism have been witnessed by the soul. It is akind of a divine battery that never exhausts its power or capacity during individual life and re-birth ascompared to manmade battery which loses its strength with time in working of instruments/devices.The battery has to be replaced in order to make the device in working condition. We hope that presentstudy will provide the scientific basis in understanding the embedded relationship of soul, mann in thefunctioning of human and body.

Effect of prenatal exposure of alcohol in the morphology of developing rat embryo.

The objective this study was to observe the morphological changes in developing rat embryo exposed to alcohol in utero. Virgin female Wistar rats in experimental group (n=15) were given 20% (v/v) alcohol two weeks before mating and throughout the gestational period through oral route. The controls (n=15) were also maintained and were given the tap water. On gestational day 15 (GD15) and 19 (GD19), five rats from each group were sacrificed by cervical dislocation and the abdomen was incised to expose the uterine horn. The number of implantation sites and resorptions were counted and recorded. The body weight and length of the fetuses were also recorded. The litter size and body weight of the newborn were also recorded at the time of birth from the remaining dam. The incidence of resorption was higher in alcohol treated group than in control which was found to be 25% and 8.7% at days 15 and 19 respectively. The body weight and length of fetuses were found to be decreased and was significant at GD15 (p<0.001 for weight and p<0.05 for length). Similarly, the litter size and body weight of newborn were also found to be decreased significantly (p<0.05 for litter size and p<0.01 for body weight). The present study shows that the maternal consumption of alcohol during pregnancy has adverse effect on fetal viability and development of growing embryo.

Role of Quercetin in Cardiovascular Diseases

Cardiovascular disease constitutes a major public health concern in industrialized nations. Over recent decades; a large body of evidence has accumulated indicating that oxidative stress induced free radicals play a critical role in cellular processes implicated in atherosclerosis and many other heart diseases. However a diet high in antioxidants is associated with a reduced risk of cardiovascular disease. The compound quercetin is a dietary antioxidant with a polyphenolic structure that is present in many foods; such as onion; apples; wine and tea. An increased intake of quercetin has been correlated with a decrease in the risk of cardiovascular diseases. Quercetin has been reported to exhibit a wide range of biological and pharmacological effects in animals and man besides its antioxidative and free radical scavenging actions. This paper reviews various steps of oxidative stress mediated atherogenesis and their signaling pathways and also emphasizes the role of quercetin in controlling oxidative stress and reducing the incidence of cardiovascular diseases

Utility of phenotypic dermal indices in the detection of Down syndrome patients.

Down syndrome (DS) is the most common cause of mental retardation. The frequency of DS patients is about 1:800 and is mainly because of the presence of extra copy of chromosome number 21. Dermatoglyphic has been well established as a diagnostic aid in number of diseases having hereditary basis. Dermatoglyphic data was obtained by the use of ink and prints on a paper, from 15 cytogenetically confirmed patients of Down syndrome attending to the genetic clinic at BPKIHS. The data were correlated and compared with equal number of controls. Dermatoglyphic prints were used to evaluate the variation in the fingerprint patterns, the presence of simian crease and the difference in 'atd' 'dat' and 'adt' angles between the control and the DS patients. The results showed that both the 'atd' and 'adt' angles differed significantly from the control group. The dactylography study revealed higher incidence of loops and lower incidence of whorls in the DS patients as compared with the controls. This method is non-invasive and cost effective. The observed changes in the 'atd' and 'adt' angles plus the fingerprint patterns in the dermatoglyphic study proved that this simple technique could be a valuable tool for selecting patients of DS for cytogenetics analysis.

Quercetin: a Versatile Flavonoid

Associative evidence from observational and intervention studies in human subjects shows that a diet including plant foods (particularly fruit and vegetables rich in antioxidants) conveys health benefits. There is no evidence that any particular nutrient or class of bioactive substances makes a special contribution to these benefits. Flavonoids occur naturally in fruits; vegetables and beverages such as tea and wine. Quercetin is the major flavonoid which belongs to the class called flavonols. Quercetin is found in many common foods including apples; tea; onions; nuts; berries; cauliflower; cabbage and many other foods. Quercetin provides many health promoting benefits; including improvement of cardiovascular health; eye diseases; allergic disorders; arthritis; reducing risk for cancers and many more. The main aim of this review is to obtain a further understanding of the reported beneficial health effects of Quercetin; its pharmacological effects; clinical application and also to evaluate its safety

Effect of low voltage on electrical properties of eye lens.

In the present study, the Cole-cole plot of lens tissue has been drawn using AC impedance system (EG and G PARC Model 318) in the frequency range 10 mHz to 10 Hz at low voltage stress. The impedus locus between real part (Z') and imaginary part (Z") of complex impedance of lens was examined. Results showed that the extracellular resistance (Re), distribution factor (alpha) and depressed angle (theta) were significantly varied at experimental low voltages. An attempt has been made to explain the electrical data of voltage-tissue interaction on the basis of solid state biophysics.

Near ultraviolet radiation induced changes in goat lens.

The possibility that the ultraviolet radiation from sunlight and other ambient sources as a major causative factor for the onset of cataract processes and photolytic changes of the eye lens constituents was studied. Normal goat lenses exposed in vitro to near UV radiation in the region of 315-400 nm (UV-A) revealed distinct morphological changes in the ultrastructure, increase in the inorganic elements; C, H, N, and a sharp shift in the intrinsic fluorescence spectra. UV exposure resulted in an alteration in the lambda max of the excitation spectra, a red shift in the emission absorption maxima and also an increase in the absolute fluorescence intensity. Scanning electron microscopic study showed a significant increase in the interfibrillar distances of the lens structural proteins. It is argued that the UV light induced covalent modifications of the lens proteins and their aggregations might have occurred due to the generation of photolytic products which then lead to oxidative damages.