ABSTRACT
Background: Self-medication is becoming a common type of self-care behavior among the population of many countries. Obtaining and consuming drugs without the advice of physician either for diagnosis, prescription or surveillance is called self-medication. The objectives of the study were to study prevalence and existing pattern of self-medication and its determinants among the medical students.Methods: A cross sectional descriptive study was conducted involving 200 medical students by systemic random sampling method using pretested semi-structured proforma. Analysis was done using SPSS and results were presented. Chi square and odds ratio (OR) was used as statistical tool.Results: Out of 200 students, 66.5% students were from 22-24 years of age group (mean age 20.2±1.4 years, p<0.05). Prevalence of self-medication was 93%, of which 53.8% were girls and 46.2% were boys (p>0.05). Majority of the students (95.2%) were self-medicating with allopathy drugs. 51.6% responded that they were getting quick relief with self-medication. 82% were aware about the possible adverse effects (OR 0.5, p>0.05). Self-medication was practiced by 78% students for upper respiratory tract infection, headache (70%), fever (67.7%) and gastrointestinal upset (36%). Majority (83%) students consumed paracetamol tablet for various health related reasons followed by cough syrups (55.3%), nonsteroidal anti-inflammatory drugs (54.3%), antibiotics (23.1%).Conclusions: Prevalence of self-medication was high in spite of awareness of possible adverse effects amongst students. Also, the knowledge of selection of appropriate drug for self-medication was observed to be poor.
ABSTRACT
Background: Adverse drug reactions (ADR) are the fourth leading cause of mortality and a great concern in therapeutics. Pharmacovigilance is more important in India as the health care system is inadequate with poor doctor-patient ratio, high incidence of self-medication, and presence of counterfeit drugs. The present study was conducted with the aim of analyzing the pattern of ADR occurring in a rural tertiary care hospital with a newly established pharmacovigilance center and to identify the most frequent ADRs, common drugs implicated and severity of reactions. Methods: A non-interventional observational prospective study was conducted over a year. The red boxes for dropping the filled yellow ADR forms were installed in all the wards and outpatient departments. Additional information and missing data were obtained personally by either consulting the physician or through case sheets. Results: The most common class of drugs implicated in the causation of ADRs was antimicrobials (52%), followed by drugs acting on the central nervous system. The most commonly observed ADRs were dermatological Type B reactions. The majority of the reactions belonged to possible or probable category, but no reaction was categorized as definite. Conclusion: Dermatological reactions are the most common ADR occurring in our hospital and antimicrobials are the most common causative drugs. The reporting rate was adequate, and there is still a need for increasing the awareness and knowledge about ADR reporting system and pharmacovigilance for promoting the safe use of drugs.
ABSTRACT
Background: Diabetes along with hypertension is a very common ailment afflicting millions of people worldwide. The socio-economic stress caused by the morbidity and mortality associated with it is mind boggling. Hence, this study was undertaken to study the utilization of antihypertensive drugs in hypertensive diabetic patients. Methods: A prospective study was conducted on 100 hypertensive diabetic patients aged between 18 and 90 years of either gender attending Basaveshwar Teaching and General Hospital, Kalaburagi. The data collected were statistically analyzed and presented as counts and percentages. Results: In our study, we found that majority (63%) were male patients and majority belonged to 51-70 years age group. The majority of the patients were prescribed angiotensin converting enzyme inhibitors (ACEIs) alone (19%), followed by a combination of ACEIs and calcium channel blockers (9%). The generic prescribing was only 23%, and patient’s knowledge of correct dosage was 64%. Conclusion: In this study, it has been observed that the antihypertensives drugs were prescribed rationally, but the generic prescribing was only 23% which is inappropriate prescribing behavior. Hence, physicians should be educated to prescribe drugs in the generic name so that the cost of drugs is reduced.